Description

4(1H)-Quinolinone, 2,3-Dihydro-2-Methyl-, (2S)- is a high-purity, chiral organic compound belonging to the quinolinone class, serving as a critical chiral building block and intermediate in advanced synthetic chemistry. Its defined stereochemistry at the 2-position makes it particularly valuable for the development of enantiomerically pure pharmaceuticals and bioactive molecules. This compound is essential for research and development chemists in the pharmaceutical, agrochemical, and fine chemical industries seeking to incorporate complex, stereodefined heterocyclic motifs into their target molecules.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and synthesis of novel active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and anti-infective drug candidates.
• Asymmetric Synthesis: Utilized as a starting material or intermediate in catalytic asymmetric reactions to construct complex molecular architectures with high enantiomeric excess.
• Medicinal Chemistry Research: Employed in structure-activity relationship (SAR) studies and lead optimization for discovering new therapeutic agents.
• Agrochemical Development: Serves as a precursor in the synthesis of chiral herbicides, fungicides, or plant growth regulators.
• Ligand and Catalyst Development: Used to synthesize novel chiral ligands or organocatalysts for use in enantioselective transformations.
• Reference Standard: Acts as a high-purity analytical standard for quality control and method development in analytical laboratories.

Basic Information

Product Name	4(1H)-Quinolinone, 2,3-Dihydro-2-Methyl-, (2S)-
CAS No.	2082709-87-1
Molecular Formula	C10H11NO
Molecular Weight	161.20 g/mol
Synonyms	(2S)-2-Methyl-2,3-dihydro-4(1H)-quinolinone; (S)-2-Methyl-1,2,3,4-tetrahydro-4-quinolone; (S)-2-Methyl-2,3-dihydroquinolin-4(1H)-one; (2S)-2-Methyl-1,2,3,4-tetrahydroquinolin-4-one; (S)-2-Methyl-1,2,3,4-tetrahydro-4-quinolinone; (S)-2-Methyl-2,3-dihydro-1H-quinolin-4-one; (S)-2-Methyl-3,4-dihydro-2H-quinolin-4-one
EINECS	Contact for details

Quality Control

Our 4(1H)-Quinolinone, 2,3-Dihydro-2-Methyl-, (2S)- is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity assessment by HPLC, to ensure it meets the high standards required for research and development. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming identity, purity, and enantiomeric excess.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). The compound may be hygroscopic; keep the container tightly sealed in a dry environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.