Description

2-Hydroxy-4-Methoxy Phenyl Boronic Acid Pinacol Ester is a high-purity, protected boronic acid derivative essential for modern synthetic chemistry. This compound serves as a critical building block in cross-coupling reactions, enabling the efficient construction of complex molecular architectures. It is primarily utilized by researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors for drug discovery, catalyst development, and polymer synthesis.

Application

• Suzuki-Miyaura Cross-Coupling Reactions: A key reagent for forming carbon-carbon bonds in the synthesis of complex organic molecules, particularly for pharmaceutical intermediates.
• Pharmaceutical Research & Development: Used as a versatile building block in the discovery and synthesis of new active pharmaceutical ingredients (APIs) and drug candidates.
• Agrochemical Synthesis: Employed in the creation of novel herbicides, fungicides, and insecticides with improved efficacy and environmental profiles.
• Material Science & Polymer Chemistry: Facilitates the synthesis of specialty monomers and polymers for advanced materials, including OLEDs and organic semiconductors.
• Chemical Biology & Proteomics: Acts as a molecular probe or linker in bioconjugation strategies and the study of biological processes.
• Catalyst and Ligand Development: Serves as a precursor for creating novel catalysts and ligands used in asymmetric synthesis and industrial catalytic processes.

Basic Information

Product Name	2-Hydroxy-4-Methoxy Phenyl Boronic Acid Pinacol Ester
CAS No.	2072801-99-9
Molecular Formula	C₁₄H₂₁BO₄
Molecular Weight	264.13 g/mol
Synonyms	(2-Hydroxy-4-methoxyphenyl)boronic acid pinacol ester; 2-Methoxy-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenol; 4-Methoxy-2-hydroxyphenylboronic acid pinacol ester; Pinacol (2-hydroxy-4-methoxyphenyl)boronate; B-(2-Hydroxy-4-methoxyphenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; 2-Hydroxy-4-methoxybenzeneboronic acid pinacol ester; Boronic acid, B-(2-hydroxy-4-methoxyphenyl)-, 1,1-dimethylethyl ester (9CI)
EINECS	Contact for details

Quality Control

Our 2-Hydroxy-4-Methoxy Phenyl Boronic Acid Pinacol Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing including HPLC, NMR, and IR spectroscopy to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment. We adhere to cGMP principles where applicable to support our customers in regulated industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from incompatible materials such as strong acids and strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥97.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.