Description

1-Boc-Piperidine-2-Boronic Acid Pinacol Ester is a high-purity, protected boronic acid derivative essential for modern synthetic organic chemistry, particularly in cross-coupling reactions. This compound serves as a critical building block for the efficient and selective construction of complex molecules, enabling the development of novel pharmaceuticals and advanced materials. It is primarily utilized by research chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs) via Suzuki-Miyaura cross-coupling reactions.
• Medicinal Chemistry Research: Used in the discovery and optimization of new drug candidates, particularly for creating diverse compound libraries.
• Agrochemical Synthesis: Employed in the development of novel herbicides, fungicides, and insecticides requiring complex amine-boronate structures.
• Ligand and Catalyst Development: Serves as a starting material for synthesizing specialized ligands and organometallic catalysts.
• Material Science: Used in the creation of organic electronic materials and polymers with tailored properties.
• Custom Synthesis and Contract Manufacturing: A vital reagent for CDMOs (Contract Development and Manufacturing Organizations) producing bespoke organic compounds.

Basic Information

Product Name	1-Boc-Piperidine-2-Boronic Acid Pinacol Ester
CAS No.	2071192-58-8
Molecular Formula	C16H30BNO4
Molecular Weight	311.23 g/mol
Synonyms	tert-Butyl 2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)piperidine-1-carboxylate; 1-Boc-2-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)piperidine; 1-(tert-Butoxycarbonyl)-2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)piperidine; N-Boc-2-Piperidineboronic Acid Pinacol Ester; 2-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-1-piperidinecarboxylic Acid 1,1-Dimethylethyl Ester; Piperidine-2-boronic acid pinacol ester, N-Boc-protected
EINECS	Contact for details

Quality Control

Our 1-Boc-Piperidine-2-Boronic Acid Pinacol Ester is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity suitable for research and development applications. Each lot is analyzed using advanced techniques including NMR (1H, 13C, 11B), HPLC, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C under an inert atmosphere (e.g., nitrogen or argon) due to its hygroscopic (moisture-sensitive) nature. Allow the sealed container to reach room temperature before opening to prevent moisture condensation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.