Description

3-Hydroxy-5-(Trifluoromethyl)-2,3-Dihydrobenzothiophene 1,1-Dioxide is a high-value, advanced pharmaceutical intermediate characterized by its unique benzothiophene dioxide core and trifluoromethyl functionality. This compound is critical for research and development in medicinal chemistry, offering a versatile scaffold for creating novel active pharmaceutical ingredients (APIs). It is primarily sought after by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in the synthesis of complex molecules for therapeutic applications.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly in central nervous system (CNS) and anti-inflammatory research.
• Medicinal Chemistry Research: Used as a core scaffold for structure-activity relationship (SAR) studies due to its benzothiophene dioxide moiety.
• Fluorinated Compound Synthesis: Serves as a precursor for introducing the metabolically stable trifluoromethyl group into target molecules.
• Agrochemical Development: Potential intermediate in the research and synthesis of advanced crop protection agents.
• Material Science Research: Investigated for its potential in creating specialty polymers or organic electronic materials.
• Contract Research & Manufacturing (CRAM): Supplied to organizations providing custom synthesis and process development services.

Basic Information

Product Name	3-Hydroxy-5-(Trifluoromethyl)-2,3-Dihydrobenzothiophene 1,1-Dioxide
CAS No.	2070896-47-6
Molecular Formula	C9H7F3O3S
Molecular Weight	252.21 g/mol
Synonyms	5-(Trifluoromethyl)-3-hydroxy-2,3-dihydro-1-benzothiophene 1,1-dioxide; 3-Hydroxy-5-(trifluoromethyl)-2,3-dihydrobenzo[b]thiophene 1,1-dioxide; 2,3-Dihydro-3-hydroxy-5-(trifluoromethyl)benzothiophene 1,1-dioxide; 3-Hydroxy-5-trifluoromethyl-2,3-dihydrobenzothiophene-1,1-dioxide; 2070896-47-6; 3-Hydroxy-5-(trifluoromethyl)-2,3-dihydro-1-benzothiophene-1,1-dioxide
EINECS	Contact for details

Quality Control

Our 3-Hydroxy-5-(Trifluoromethyl)-2,3-Dihydrobenzothiophene 1,1-Dioxide is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. We provide a detailed Certificate of Analysis (COA) with every shipment to ensure traceability and compliance with your research or production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.