Description

2-(Diiodomethyl)-4,4,5,5-Tetramethyl-1,3,2-Dioxaborolane is a high-value organoboron building block featuring a reactive diiodomethyl group. This compound is critical for advanced organic synthesis, enabling the introduction of boron and halogen functionalities in a single step. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and materials science industries for constructing complex molecular architectures.

Application

• Suzuki-Miyaura Cross-Coupling Precursor: Serves as a versatile boronic ester precursor for palladium-catalyzed cross-coupling reactions to form carbon-carbon bonds.
• Pharmaceutical Intermediate: Used in the synthesis of active pharmaceutical ingredients (APIs) and complex bioactive molecules, particularly those requiring halogenated boronates.
• Agrochemical Synthesis: Employed in the research and development of novel herbicides, fungicides, and insecticides.
• Functional Material Development: A key reagent in the creation of organic electronic materials, such as OLEDs and semiconductors, where precise boron incorporation is needed.
• Chemical Biology Probes: Utilized for synthesizing tagged molecules and probes for imaging and diagnostic applications.
• Organic Synthesis Building Block: Facilitates sequential functionalization strategies in multi-step synthetic routes due to its dual reactive sites.

Basic Information

Product Name	2-(Diiodomethyl)-4,4,5,5-Tetramethyl-1,3,2-Dioxaborolane
CAS No.	2066512-27-2
Molecular Formula	C7H13BIO2
Molecular Weight	337.90 g/mol
Synonyms	2-(Diiodomethyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; (Diiodomethyl)boronic acid pinacol ester; Pinacol (diiodomethyl)boronate; 1,3,2-Dioxaborolane, 2-(diiodomethyl)-4,4,5,5-tetramethyl-; Diiodomethylboronic acid pinacol ester; B-(Diiodomethyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane
EINECS	Contact for details

Quality Control

Every batch of 2-(Diiodomethyl)-4,4,5,5-Tetramethyl-1,3,2-Dioxaborolane is manufactured and tested under strict quality management systems. We ensure high purity and consistency through advanced analytical techniques including NMR, HPLC, and GC-MS. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at 2-8°C to minimize oxidation and degradation. Keep the container in a cool, dry, and well-ventilated place, away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.