Description

4,4,5,5-Tetramethyl-2-(2,4,5-Trimethylthiophen-3-Yl)-1,3,2-Dioxaborolane is a high-purity, advanced boronic ester derivative, specifically designed as a critical building block in modern synthetic chemistry. Its value lies in enabling precise and efficient cross-coupling reactions, which are fundamental for constructing complex molecular architectures. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and materials science industries who require reliable, high-quality intermediates for drug discovery, advanced polymer synthesis, and the development of organic electronic materials.

Application

• Pharmaceutical Intermediate: A key precursor in Suzuki-Miyaura cross-coupling reactions for synthesizing novel active pharmaceutical ingredients (APIs) and drug candidates.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and insecticides requiring specific thiophene-boronate structures.
• Organic Electronic Materials: Serves as a monomer or building block for conjugated polymers and small molecules used in OLEDs, OFETs, and organic photovoltaics.
• Ligand and Catalyst Development: Employed in the research and synthesis of novel ligands for transition metal catalysis and organoboron catalysts.
• Chemical Biology & Proteomics: Utilized in the synthesis of molecular probes and bioconjugation reagents for studying biological systems.
• Advanced Material Research: A foundational component in creating metal-organic frameworks (MOFs) and other functional materials with tailored properties.

Basic Information

Item	Detail
Product Name	4,4,5,5-Tetramethyl-2-(2,4,5-Trimethylthiophen-3-Yl)-1,3,2-Dioxaborolane
CAS No.	2064117-97-9
Molecular Formula	C15H25BO2S
Molecular Weight	280.24 g/mol
Synonyms	2-(2,4,5-Trimethylthiophen-3-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; 3-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-2,4,5-trimethylthiophene; Pinacol (2,4,5-Trimethyl-3-thienyl)boronate; (2,4,5-Trimethylthiophen-3-yl)boronic acid pinacol ester; Trimethylthiophene pinacol boronate ester; CAS 2064117-97-9
EINECS	Contact for details

Quality Control

Our production of 4,4,5,5-Tetramethyl-2-(2,4,5-Trimethylthiophen-3-Yl)-1,3,2-Dioxaborolane adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing key parameters such as assay, identity, and impurity profiles. We support cGMP and ISO 9001 compliant manufacturing practices to meet the exacting standards of our global clientele in research and regulated industries.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at 2-8°C or as specified on the label or COA. Due to its hygroscopic and easily oxidized nature, the container must be kept tightly sealed in a cool, dry place after opening to minimize exposure to moisture and air. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Purity (NMR)	Conforms
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.