Description

16,25-Di-o-Acetylcucurbitacin F is a high-purity, semi-synthetic derivative of the bioactive cucurbitacin triterpenoid family, valued for its role as a critical reference standard and research-grade biochemical. This compound is essential for advancing studies in natural product chemistry, pharmacology, and drug discovery, particularly in the investigation of anti-cancer and anti-inflammatory pathways. It is primarily utilized by research institutions, pharmaceutical R&D laboratories, and fine chemical manufacturers focused on developing novel therapeutic agents.

Application

• Pharmaceutical Research & Development: Serves as a key reference standard and active pharmaceutical ingredient (API) intermediate for preclinical studies targeting cancer and inflammatory diseases.
• Biochemical Assay Development: Used as a precise analytical standard in HPLC and LC-MS methods to quantify cucurbitacin derivatives in complex matrices.
• Natural Product Chemistry: Acts as a crucial intermediate for the semi-synthesis of novel cucurbitacin analogs with potentially enhanced bioactivity or pharmacokinetic profiles.
• Academic Research: Employed in university and institutional labs to study cell signaling pathways, apoptosis induction, and structure-activity relationships (SAR) of triterpenoids.
• Quality Control & Standardization: Provides a certified material for the quality assurance and standardization of herbal extracts or products containing cucurbitacin compounds.

Basic Information

Product Name	16,25-Di-o-Acetylcucurbitacin F
CAS No.	2062685-10-1
Molecular Formula	C34H48O9
Molecular Weight	600.75 g/mol
Synonyms	16,25-Di-O-acetylcucurbitacin F; 16α,25-Diacetylcucurbitacin F; Cucurbitacin F 16,25-diacetate; (23E)-25-(Acetyloxy)-16-[(acetyloxy)methyl]-6β-hydroxy-3-(hydroxymethyl)-9,13-dimethyl-2,10-dioxo-7,8,9,11,12,13,15,16-octahydro-2H-cyclopenta[a]phenanthren-17-yl acetate; 16,25-Di-O-acetyl-cucurbitacin F
EINECS	Contact for details

Quality Control

Our 16,25-Di-o-Acetylcucurbitacin F is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods (NMR, MS), to ensure it meets the high standards required for research applications. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a dry environment. The product is light-sensitive and should be handled accordingly to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Assay	≥ 97.0%
Loss on Drying	≤ 2.0%
Residue on Ignition	≤ 0.5%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 5.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.