Description

4H-Pyrazolo[5,1-C][1,4]Oxazine, 6,7-Dihydro-3-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)- is a high-value, advanced pharmaceutical intermediate and building block featuring a pyrazolo-oxazine core functionalized with a pinacol boronate ester group. This compound matters because it serves as a crucial coupling partner in Suzuki-Miyaura cross-coupling reactions, enabling the efficient synthesis of complex heterocyclic scaffolds essential for modern drug discovery. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries who are developing new active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates targeting various therapeutic areas.
• Suzuki-Miyaura Cross-Coupling: Essential boron reagent for forming carbon-carbon bonds to construct complex biaryl and heteroaryl structures.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides with improved efficacy.
• Material Science: Precursor for creating organic electronic materials, such as those used in OLEDs and semiconductors.
• Chemical Biology & Probe Development: Utilized in creating molecular probes for studying biological pathways and enzyme functions.
• Process Chemistry & Scale-up: Serves as a reliable starting material for optimizing and scaling the production of target molecules.

Basic Information

Product Name	4H-Pyrazolo[5,1-C][1,4]Oxazine, 6,7-Dihydro-3-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)-
CAS No.	2057507-08-9
Molecular Formula	C15H23BN2O3
Molecular Weight	290.17 g/mol
Synonyms	6,7-Dihydro-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-4H-pyrazolo[5,1-c][1,4]oxazine; 3-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-6,7-dihydro-4H-pyrazolo[5,1-c][1,4]oxazine; 4H-Pyrazolo[5,1-c][1,4]oxazine, 6,7-dihydro-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-; 2057507-08-9; Boronic acid, B-(6,7-dihydro-4H-pyrazolo[5,1-c][1,4]oxazin-3-yl)-, pinacol ester; 3-Pinacolatoboryl-6,7-dihydro-4H-pyrazolo[5,1-c][1,4]oxazine
EINECS	Contact for details

Quality Control

Our 4H-Pyrazolo[5,1-C][1,4]Oxazine, 6,7-Dihydro-3-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)- is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity, typically ≥95% (HPLC). Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity confirmation via spectroscopic methods (NMR, IR, MS), and impurity profiles. We adhere to cGMP guidelines where applicable to support our clients' regulatory filings.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C or as specified on the label. This product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (argon or nitrogen) when possible to maintain stability and prevent decomposition.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.