Description

Propargyl-Peg9-Bromide is a specialized bifunctional PEG linker featuring a terminal propargyl group and a reactive bromide. This compound is essential for creating stable, hydrophilic spacers in bioconjugation and materials science, enabling precise and efficient cross-linking via click chemistry and nucleophilic substitution. It is primarily utilized by researchers and manufacturers in the pharmaceutical, biotechnology, and advanced materials sectors for developing drug delivery systems, diagnostic probes, and functional polymers.

Application

• As a key reagent in click chemistry for the synthesis of antibody-drug conjugates (ADCs) and protein-polymer hybrids.
• As a PEG-based linker to introduce hydrophilicity and improve solubility in prodrug design and nanoparticle functionalization.
• For the site-specific modification of peptides, oligonucleotides, and small molecules via its reactive bromide and alkyne termini.
• In materials science for the surface modification of polymers, dendrimers, and hydrogels to impart specific biological functionalities.
• As a building block in the development of diagnostic imaging agents and biosensors.
• For creating cross-linked networks and functionalized coatings with controlled release properties.

Basic Information

Product Name	Propargyl-Peg9-Bromide
CAS No.	2055042-83-4
Molecular Formula	C₂₄H₄₅BrO₉
Molecular Weight	557.52 g/mol
Synonyms	1-Bromo-3,6,9,12,15,18,21,24,27-nonaoxahentriacont-30-yn-31-ol; Propargyl-PEG9-Br; α-Propargyl-ω-bromo-nonaethylene glycol; Bromo-PEG9-propargyl; 2-(2-(2-(2-(2-(2-(2-(2-(2-(Prop-2-yn-1-yloxy)ethoxy)ethoxy)ethoxy)ethoxy)ethoxy)ethoxy)ethoxy)ethoxy)ethyl bromide; Propargyl-O-(CH₂CH₂O)₉-CH₂CH₂Br; PEG9 Propargyl Bromide
EINECS	Contact for details

Quality Control

Our Propargyl-Peg9-Bromide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high purity and consistent performance. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided to guarantee compliance with research and development standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C. This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow viscous liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 0.5%
Molecular Weight Confirmation (MS)	Conforms

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.