Description

Ald-Ph-Peg2-Amine CAS NO 2055013-56-2 is a specialized bifunctional PEG linker featuring an aldehyde group and a primary amine, separated by a short polyethylene glycol (PEG) spacer. This compound is critical for creating stable, hydrophilic conjugates in bioconjugation and pharmaceutical development, offering controlled reactivity and improved solubility. It is an essential building block for researchers and manufacturers in biopharmaceuticals, diagnostic assay development, and advanced material science, where precise molecular tethering is required.

Application

• Bioconjugation and Antibody-Drug Conjugate (ADC) Linker: Used to covalently attach drugs, dyes, or other functional molecules to proteins, antibodies, or peptides via its amine-reactive aldehyde and thiol-reactive termini after modification.
• Surface Functionalization: Employed to modify nanoparticles, biosensors, and chromatographic media to introduce amine or aldehyde groups for further coupling reactions.
• Crosslinking Agent: Serves as a heterobifunctional crosslinker for hydrogel formation, polymer network creation, and immobilizing biomolecules on solid supports.
• Pharmaceutical Intermediate: Acts as a key synthetic intermediate in the production of targeted therapeutics and prodrugs requiring PEGylated spacers.
• Diagnostic Reagent Synthesis: Utilized in the development of enzyme-linked immunosorbent assays (ELISA), lateral flow assays, and other diagnostic tools.
• Polymer Chemistry: A monomer or modifier for synthesizing functionalized, water-soluble polymers with tailored reactive sites.

Basic Information

Product Name	Ald-Ph-Peg2-Amine
CAS No.	2055013-56-2
Molecular Formula	C15H23NO4
Molecular Weight	281.35 g/mol
Synonyms	2-[2-[2-(2-Formylphenoxy)ethoxy]ethoxy]ethanamine; 4-Formylphenyl-PEG2-amine; Amino-PEG2-benzaldehyde; Benzaldehyde-PEG2-amine; Aldehyde-PEG2-Amine (Ph); Fmoc-PEG2-CH2CH2NH2 (related precursor); Heterobifunctional PEG linker, Amine-Aldehyde; 2055013-56-2
EINECS	Contact for details

Quality Control

Every batch of Ald-Ph-Peg2-Amine is manufactured under a strict quality management system and undergoes comprehensive analytical testing to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, which includes data from HPLC, NMR, and mass spectrometry. Our quality commitment aligns with standards relevant to GMP-grade intermediates for pharmaceutical research and development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C or as indicated on the label. This product is hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation. Allow the sealed vial to equilibrate to room temperature before opening to minimize moisture ingress.

Specification

Item	Specification
Appearance	Colorless to pale yellow viscous liquid or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95%
Assay	≥ 90%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.