Description

Ald–Ph–PEG6–Acid CAS NO 2055013-55-1 is a heterobifunctional polyethylene glycol (PEG) derivative featuring an aldehyde group and a carboxylic acid group, separated by a hexaethylene glycol spacer. This compound is a critical building block for bioconjugation and linker chemistry, enabling the controlled, site-specific attachment of biomolecules, polymers, or surfaces. It is essential for researchers and manufacturers in pharmaceutical development, proteomics, and advanced material science who require precise and stable cross-linking strategies.

Application

• Bioconjugation Reagent: For site-specific coupling of peptides, proteins, or antibodies via the aldehyde group to amine-containing molecules via the carboxylic acid group, or vice-versa.
• PEGylation Linker: Serves as a functionalized spacer to PEGylate drug molecules, enhancing solubility, stability, and pharmacokinetic profiles.
• Surface Functionalization: Used to modify nanoparticles, biosensors, or chromatography media with reactive handles for further biomolecule immobilization.
• Hydrogel Formation: Acts as a cross-linking agent in the synthesis of biocompatible hydrogels for drug delivery and tissue engineering.
• Diagnostic Assay Development: Employed in the fabrication of immunoassays and biosensors by linking capture molecules to solid supports.
• ADC (Antibody-Drug Conjugate) Payload Attachment: Facilitates the construction of ADC linkers, connecting cytotoxic drugs to monoclonal antibodies.

Basic Information

Product Name	Ald–Ph–PEG6–Acid
CAS No.	2055013-55-1
Molecular Formula	C31H52O12
Molecular Weight	616.74 g/mol
Synonyms	4-Formylbenzyl-PEG6-acid; 4-Formyl-PEG6-C2-acid; Aldehyde-PEG6-acid; Fmoc-PEG6-CHO; (4-Formylbenzyl)undecaethylene glycol)acetic acid; 2-[2-[2-[2-[2-[2-[2-[2-[2-[2-(4-Formylphenoxy)ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]acetic acid; α-Acetic acid-ω-(4-formylbenzyl) hexaethylene glycol
EINECS	Contact for details

Quality Control

Our Ald–Ph–PEG6–Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR for structural confirmation, and titration for functional group quantification, to ensure it meets the high standards required for research and biopharmaceutical applications. Certificates of Analysis (COA) with detailed specifications are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) to prevent oxidation and hydrolysis. The product is hygroscopic (moisture-sensitive) and should be handled in a dry environment. Allow the sealed vial to equilibrate to room temperature before opening to minimize moisture condensation.

Specification

Item	Specification
Appearance	White to off-white solid or viscous liquid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95%
Assay (Aldehyde Content)	≥ 90%
Assay (Acid Content)	≥ 90%
Water Content (KF)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.