Description

[(2-Chloro-4-Fluorophenyl)Methyl]Hydrazine Dihydrochloride is a high-purity, synthetically valuable organic building block primarily used in advanced pharmaceutical and agrochemical research. Its core value lies in its role as a key hydrazine-based intermediate for constructing complex heterocyclic structures and active pharmaceutical ingredients (APIs). This compound is essential for R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to develop new active compounds.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, infectious diseases, and oncology.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and insecticides, leveraging the bioactivity of the fluorinated phenylhydrazine moiety.
• Chemical Research & Development: Serves as a versatile building block for constructing pyrazole, triazole, and other nitrogen-containing heterocycles in academic and industrial research labs.
• Material Science: Potential application in the synthesis of specialty polymers, ligands for catalysis, and advanced organic electronic materials.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for scale-up and production under cGMP conditions for clinical trial materials.

Basic Information

Product Name	[(2-Chloro-4-Fluorophenyl)Methyl]Hydrazine Dihydrochloride
CAS No.	2044707-02-8
Molecular Formula	C7H9Cl2FN2
Molecular Weight	219.06 g/mol
Synonyms	1-[(2-Chloro-4-fluorophenyl)methyl]hydrazine dihydrochloride; (2-Chloro-4-fluorobenzyl)hydrazine dihydrochloride; 2-Chloro-4-fluoro-α-methylbenzylhydrazine dihydrochloride; N-[(2-Chloro-4-fluorophenyl)methyl]hydrazine dihydrochloride; 1-(2-Chloro-4-fluorobenzyl)hydrazine hydrochloride (1:2); Hydrazine, [(2-chloro-4-fluorophenyl)methyl]-, dihydrochloride
EINECS	Contact for details

Quality Control

Our [(2-Chloro-4-Fluorophenyl)Methyl]Hydrazine Dihydrochloride is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment. We support development and commercial projects requiring compliance with ICH guidelines and can supply material suitable for use under cGMP conditions.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) when opening to prevent oxidation and moisture uptake. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.