Description

5-(Tetramethyl-1,3,2-Dioxaborolan-2-Yl)-1,3-Benzothiazol-2-Amine is a high-value, organoboron-protected benzothiazole derivative, serving as a critical synthetic intermediate. Its core value lies in enabling efficient cross-coupling reactions, specifically Suzuki-Miyaura couplings, which are fundamental for constructing complex molecular architectures in advanced research and development. This compound is essential for medicinal chemists and process development scientists in the pharmaceutical and agrochemical industries, where it is used to introduce the benzothiazol-2-amine pharmacophore into target molecules for drug discovery and crop protection agents.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly those targeting neurological disorders, oncology, and infectious diseases.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides by incorporating the benzothiazole moiety.
• Material Science: A precursor for creating organic electronic materials, such as ligands for OLEDs or molecular sensors.
• Chemical Biology: Employed in the synthesis of probes and tool compounds for studying biological pathways and protein function.
• Academic & Contract Research: A versatile reagent for methodology development and complex molecule synthesis in university and CRO laboratories.

Basic Information

Product Name	5-(Tetramethyl-1,3,2-Dioxaborolan-2-Yl)-1,3-Benzothiazol-2-Amine
CAS No.	2043401-94-9
Molecular Formula	C₁₃H₁₉BN₂O₂S
Molecular Weight	278.18 g/mol
Synonyms	2-Amino-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzothiazole; 5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-1,3-benzothiazol-2-amine; 2-Amino-5-(tetramethyl-1,3,2-dioxaborolan-2-yl)benzothiazole; Benzothiazole, 2-amino-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-; 5-(Tetramethyl-1,3,2-dioxaborolan-2-yl)benzothiazol-2-amine; B-(2-Aminobenzothiazol-5-yl)boronic acid pinacol ester; 2043401-94-9
EINECS	Contact for details

Quality Control

Our 5-(Tetramethyl-1,3,2-Dioxaborolan-2-Yl)-1,3-Benzothiazol-2-Amine is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity for research and development applications. We provide comprehensive Certificates of Analysis (COA) with each batch, detailing purity and impurity profiles. Our quality commitment aligns with the standards expected in pharmaceutical development, ensuring reliable performance in sensitive cross-coupling reactions.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) when possible to prevent degradation. Keep the container tightly sealed in a desiccator for long-term storage.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.