Description

3-Bromo-4-Methylpyridine-5-Boronic Acid Pinacol Ester is a high-purity, organoboron building block essential for modern synthetic chemistry. This compound is a critical reagent in Suzuki-Miyaura cross-coupling reactions, enabling the efficient construction of complex heterocyclic scaffolds. It is primarily utilized by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and advanced intermediates.

Application

• Pharmaceutical Intermediate: A key building block for synthesizing novel drug candidates, particularly in kinase inhibitor and central nervous system (CNS) therapeutic research.
• Agrochemical Synthesis: Used in the development of new herbicides, fungicides, and insecticides with improved efficacy and selectivity.
• Material Science Research: Employed in the creation of organic electronic materials, such as ligands for OLEDs and conductive polymers.
• Chemical Biology Probes: Serves as a precursor for labeling reagents and molecular probes used in diagnostic and bioimaging applications.
• Catalyst Ligand Development: Utilized in the synthesis of novel ligand systems for transition metal catalysis.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) producing bespoke compounds for clients.

Basic Information

Product Name	3-Bromo-4-Methylpyridine-5-Boronic Acid Pinacol Ester
CAS No.	2043397-75-5
Molecular Formula	C₁₂H₁₇BBrNO₂
Molecular Weight	298.00 g/mol
Synonyms	5-Bromo-6-methylpyridine-3-boronic acid pinacol ester; (3-Bromo-4-methylpyridin-5-yl)boronic acid pinacol ester; 3-Bromo-4-methylpyridine-5-boronic acid neopentyl glycol ester (common alternative); 5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-3-bromo-4-methylpyridine; B-(3-Bromo-4-methyl-5-pyridinyl)boronic acid pinacol ester; 2043397-75-5; Pyridine boronic ester derivative
EINECS	Contact for details

Quality Control

Our 3-Bromo-4-Methylpyridine-5-Boronic Acid Pinacol Ester is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high chemical purity and structural integrity. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (argon or nitrogen) for long-term storage and when opening the container to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥97.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.