Description

7-Methyl-2-Oxoindoline-5-Boronic Acid Pinacol Ester is a high-purity, advanced pharmaceutical intermediate and versatile building block for organic synthesis. Its core value lies in its role as a protected boronic acid derivative, enabling critical carbon-carbon bond formation reactions like the Suzuki-Miyaura cross-coupling. This compound is essential for researchers and manufacturers in medicinal chemistry, particularly those developing novel small-molecule drug candidates and complex agrochemicals.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of complex heterocyclic compounds for drug discovery programs.
• Suzuki-Miyaura Cross-Coupling Reactions: Serves as a stable, air-handleable boronic ester reagent for constructing biaryl and other conjugated systems.
• Medicinal Chemistry Research: Used in the design and synthesis of potential therapeutic agents targeting various diseases.
• Agrochemical Synthesis: Intermediate in the development of new active ingredients for crop protection products.
• Material Science: Building block for creating organic electronic materials and functional polymers.
• Chemical Biology Probes: Utilized in the synthesis of molecular probes for studying biological processes.

Basic Information

Product Name	7-Methyl-2-Oxoindoline-5-Boronic Acid Pinacol Ester
CAS No.	2036075-04-2
Molecular Formula	C16H22BNO3
Molecular Weight	287.16 g/mol
Synonyms	5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-7-methylindolin-2-one; 7-Methyl-2-oxo-2,3-dihydro-1H-indole-5-boronic acid pinacol ester; 7-Methyl-2-oxoindoline-5-boronic acid, pinacol ester; 5-Borono-7-methylindolin-2-one pinacol ester; 7-Methyl-2-oxindole-5-boronic acid pinacol ester; 7-Methyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)indolin-2-one
EINECS	Contact for details

Quality Control

Our 7-Methyl-2-Oxoindoline-5-Boronic Acid Pinacol Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and LC-MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all relevant specifications. Our quality commitment supports applications in GMP and research environments where material integrity is paramount.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic and moisture-sensitive nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation and oxidation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥97.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%
Single Unknown Impurity (HPLC)	≤0.5%
Total Impurities (HPLC)	≤3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.