Description

1-(Cyclopropylmethyl)Pyrazole-5-Boronic Acid Pinacol Ester is a high-purity, advanced pharmaceutical intermediate and versatile building block in organic synthesis. Its core value lies in enabling efficient Suzuki-Miyaura cross-coupling reactions, a critical step for constructing complex molecules in medicinal chemistry. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and material science industries developing new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in oncology and central nervous system (CNS) drug discovery.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides with improved efficacy.
• Material Science: Serves as a precursor for creating organic electronic materials, such as those used in OLEDs and organic photovoltaics.
• Chemical Research & Development: A crucial reagent in academic and industrial R&D labs for constructing complex heterocyclic compounds and exploring new chemical spaces.
• Ligand Synthesis: Employed in the preparation of specialized ligands for catalysis and metal-organic frameworks (MOFs).

Basic Information

Product Name	1-(Cyclopropylmethyl)Pyrazole-5-Boronic Acid Pinacol Ester
CAS No.	2019997-41-0
Molecular Formula	C14H23BN2O2
Molecular Weight	262.16 g/mol
Synonyms	5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-1-(cyclopropylmethyl)-1H-pyrazole; 1-(Cyclopropylmethyl)-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole; 1-(Cyclopropylmethyl)-1H-pyrazole-5-boronic acid pinacol ester; 1-Cyclopropylmethyl-1H-pyrazol-5-ylboronic acid pinacol ester; Pyrazole-5-boronic acid pinacol ester, 1-(cyclopropylmethyl)-; 2019997-41-0; Borate complex with 1-(cyclopropylmethyl)-1H-pyrazol-5-ylboronic acid and pinacol
EINECS	Contact for details

Quality Control

Our 1-(Cyclopropylmethyl)Pyrazole-5-Boronic Acid Pinacol Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high purity and batch-to-batch consistency suitable for sensitive coupling reactions. Comprehensive Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.