Description

6-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Imidazo[1,2-A]Pyrimidine CAS NO 2018362-18-8 is a high-purity, advanced pharmaceutical intermediate featuring a pinacol boronate ester functional group. This compound is a critical building block in modern medicinal chemistry, enabling efficient cross-coupling reactions for the synthesis of complex heterocyclic molecules. It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in the development of novel active pharmaceutical ingredients (APIs) and drug candidates.

Application

• Suzuki-Miyaura Cross-Coupling Reactions: As a key boronic ester reagent for constructing carbon-carbon bonds in complex molecule synthesis.
• Pharmaceutical Research & Development: Serves as a versatile intermediate in the discovery and process development of new therapeutic agents.
• Agrochemical Synthesis: Used in the creation of novel pesticides and herbicides that require specific heterocyclic architectures.
• Material Science: A precursor for organic electronic materials and functional polymers where the imidazopyrimidine core is advantageous.
• Chemical Biology & Proteomics: Employed in the synthesis of molecular probes and tool compounds for target identification and validation.

Basic Information

Product Name	6-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Imidazo[1,2-A]Pyrimidine
CAS No.	2018362-18-8
Molecular Formula	C14H18BN3O2
Molecular Weight	271.13 g/mol
Synonyms	6-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)imidazo[1,2-a]pyrimidine; Imidazo[1,2-a]pyrimidine-6-boronic acid pinacol ester; 6-(Pinacolboryl)imidazo[1,2-a]pyrimidine; 6-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-imidazo[1,2-a]pyrimidine; 2018362-18-8; Imidazo[1,2-a]pyrimidine-6-boronic acid, pinacol ester; 6-(Pinacolatoboryl)imidazo[1,2-a]pyrimidine
EINECS	Contact for details

Quality Control

Our production of 6-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Imidazo[1,2-A]Pyrimidine adheres to stringent quality management protocols. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure high chemical purity and structural identity. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment to support your quality and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) to prevent moisture absorption and degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.