Description

4,4,5,5-Tetramethyl-2-(Naphtho[1,2-B]Benzofuran-7-Yl)-1,3,2-Dioxaborolane is a high-purity, advanced boronic ester derivative, serving as a critical building block in modern synthetic chemistry. Its value lies in enabling precise carbon-carbon bond formation, which is fundamental for constructing complex molecular architectures. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and materials science industries, particularly for developing novel active ingredients and functional organic materials.

Application

• Pharmaceutical Intermediate: A key reagent in Suzuki-Miyaura cross-coupling reactions for synthesizing novel drug candidates and active pharmaceutical ingredients (APIs).
• Agrochemical Synthesis: Used in the research and development of advanced pesticides, herbicides, and fungicides with specific activity profiles.
• Organic Light-Emitting Diodes (OLEDs): Acts as a precursor for constructing complex organic semiconductors and emissive layer materials in display and lighting technologies.
• Material Science Research: Employed in the synthesis of conjugated polymers, liquid crystals, and other functional organic materials for electronic applications.
• Chemical Biology & Proteomics: Utilized as a handle for bioconjugation and the development of chemical probes for target identification and validation.
• Academic & Process R&D: Serves as a versatile building block in methodological development and scale-up studies for complex molecule synthesis.

Basic Information

Product Name	4,4,5,5-Tetramethyl-2-(Naphtho[1,2-B]Benzofuran-7-Yl)-1,3,2-Dioxaborolane
CAS No.	2007912-83-4
Molecular Formula	C22H23BO3
Molecular Weight	346.23 g/mol
Synonyms	7-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)naphtho[1,2-b]benzofuran; Naphtho[1,2-b]benzofuran-7-boronic acid pinacol ester; 7-(Pinacolatoboryl)naphtho[1,2-b]benzofuran; Naphthobenzofuran-7-ylboronic acid pinacol ester; 7-Naphtho[1,2-b]benzofuranylboronic acid pinacol ester; 2007912-83-4; Naphthofuran boronic ester
EINECS	Contact for details

Quality Control

Our 4,4,5,5-Tetramethyl-2-(Naphtho[1,2-B]Benzofuran-7-Yl)-1,3,2-Dioxaborolane is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and elemental analysis, to ensure high purity and batch-to-batch consistency suitable for demanding R&D and scale-up applications. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥97.0% (Area %)
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.