Description

Ethyl 2-[4-(2-Ethoxy-2-Oxoethyl)Phenyl]-2,2-Difluoroacetate is a high-purity, specialty organic ester featuring a difluoroacetate moiety and a phenylacetic acid derivative structure. This compound serves as a critical advanced pharmaceutical intermediate (API) and a versatile building block in modern synthetic chemistry. It is primarily required by R&D and production teams in the pharmaceutical, agrochemical, and specialty chemical industries for developing novel active ingredients.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of complex drug molecules, particularly those requiring difluoromethyl or difluoroacetate functional groups.
• Agrochemical Synthesis: Used in the research and development of new-generation herbicides and pesticides with enhanced activity and selectivity.
• Material Science Precursor: Serves as a monomer or modifier in the production of specialty polymers and advanced materials with unique properties.
• Organic Synthesis Reagent: A valuable reagent for introducing the 2,2-difluoroacetate moiety into target molecules in medicinal and process chemistry.
• Fluorine Chemistry Research: Essential for academic and industrial research focused on organofluorine compounds and their applications.

Basic Information

Product Name	Ethyl 2-[4-(2-Ethoxy-2-Oxoethyl)Phenyl]-2,2-Difluoroacetate
CAS No.	2006277-16-1
Molecular Formula	C14H16F2O4
Molecular Weight	286.27 g/mol
Synonyms	Ethyl 4-[2-(Ethoxycarbonyl)-2,2-difluoroacetyl]phenylacetate; 2,2-Difluoro-2-[4-(2-ethoxy-2-oxoethyl)phenyl]acetic Acid Ethyl Ester; Ethyl 2,2-Difluoro-2-[4-(2-ethoxy-2-oxoethyl)phenyl]acetate; [4-(2-Ethoxy-2-oxoethyl)phenyl](difluoro)acetic Acid Ethyl Ester; CAS 2006277-16-1; Difluoroacetate Ester Intermediate
EINECS	Contact for details

Quality Control

Our Ethyl 2-[4-(2-Ethoxy-2-Oxoethyl)Phenyl]-2,2-Difluoroacetate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the stringent requirements for pharmaceutical and fine chemical applications. Certificates of Analysis (COA) with detailed chromatographic data are provided for each lot.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from strong bases and incompatible materials. The container should be kept tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (HPLC/IR)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any Single Unknown Impurity	≤ 0.5%
Residual Solvents (GC)	Meets ICH Q3C guidelines
Water Content (KF)	≤ 0.5% w/w

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.