Description

2-Chloro-4-(4-Morpholinylcarbonyl)Benzeneboronic Acid is a high-value boronic acid derivative that serves as a critical building block in modern synthetic chemistry. Its molecular architecture, featuring both a boronic acid group and a morpholine-carbonyl moiety, makes it an essential reagent for constructing complex molecules via cross-coupling reactions. This compound is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key precursor in Suzuki-Miyaura cross-coupling reactions for the synthesis of biaryl structures found in drug candidates.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides requiring specific boronic acid coupling steps.
• Material Science: Employed in the synthesis of organic electronic materials and advanced polymers where precise molecular architecture is required.
• Chemical Biology & Proteomics: Acts as a versatile handle for bioconjugation and the development of enzyme inhibitors or activity-based probes.
• Catalyst Ligand Synthesis: Useful for constructing sophisticated ligand frameworks for transition metal catalysis.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs for the production of bespoke compounds and non-commercial scale-up projects.

Basic Information

Product Name	2-Chloro-4-(4-Morpholinylcarbonyl)Benzeneboronic Acid
CAS No.	2000187-73-3
Molecular Formula	C11H13BClNO4
Molecular Weight	269.49 g/mol
Synonyms	[2-Chloro-4-(morpholine-4-carbonyl)phenyl]boronic acid; (2-Chloro-4-morpholinocarbonylphenyl)boronic acid; 2-Chloro-4-(morpholin-4-ylcarbonyl)benzeneboronic acid; Boronic acid, B-[2-chloro-4-(4-morpholinylcarbonyl)phenyl]-; 2-Chloro-4-morpholin-4-ylcarbonylbenzeneboronic acid; CAS 2000187-73-3
EINECS	Contact for details

Quality Control

Our 2-Chloro-4-(4-Morpholinylcarbonyl)Benzeneboronic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) with full traceability are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.