Description

1-(3-Trifluoromethyl-Phenyl)-1H-Pyrrole-2-Carbaldehyde is a specialized fluorinated pyrrole derivative, a high-value building block in advanced organic synthesis. Its core value lies in its unique molecular structure, which combines a reactive aldehyde group with a trifluoromethylphenyl moiety, making it a critical intermediate for creating compounds with tailored electronic and steric properties. This chemical is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of novel drug candidates, especially in medicinal chemistry programs targeting central nervous system (CNS) disorders, inflammation, and oncology.
• Agrochemical Research: Used in the development of new-generation pesticides and herbicides, where the trifluoromethyl group can enhance biological activity and environmental stability.
• Material Science Precursor: Serves as a monomer or functionalizing agent in the synthesis of advanced polymers, liquid crystals, and organic electronic materials.
• Chemical Synthesis Reagent: Employed in organic synthesis for constructing complex heterocyclic frameworks via reactions like Paal-Knorr synthesis, condensation, and cross-coupling.
• Fluorine Chemistry Studies: A valuable compound for academic and industrial research into the effects of fluorine substitution on molecular reactivity and physical properties.

Basic Information

Product Name	1-(3-Trifluoromethyl-Phenyl)-1H-Pyrrole-2-Carbaldehyde
CAS No.	299169-87-2
Molecular Formula	C12H8F3NO
Molecular Weight	239.19 g/mol
Synonyms	1-[3-(Trifluoromethyl)phenyl]-1H-pyrrole-2-carboxaldehyde; 1-(3-Trifluoromethylphenyl)-1H-pyrrole-2-carbaldehyde; 2-Formyl-1-(3-trifluoromethylphenyl)pyrrole; 1H-Pyrrole-2-carboxaldehyde, 1-[3-(trifluoromethyl)phenyl]-; 1-(3-(Trifluoromethyl)phenyl)pyrrole-2-carbaldehyde; 3-Trifluoromethylphenyl pyrrole-2-carbaldehyde; α-Formyl-1-(3-trifluoromethylphenyl)pyrrole
EINECS	Contact for details

Quality Control

Our 1-(3-Trifluoromethyl-Phenyl)-1H-Pyrrole-2-Carbaldehyde is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by NMR and IR spectroscopy, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) detailing all specifications are available upon request to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its light-sensitive and easily oxidized nature, it is recommended to store the material under an inert atmosphere (e.g., nitrogen or argon) for long-term stability. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.