Description

6-(Trifluoromethyl)-2,3,4,9-Tetrahydro-1H-Carbazol-1-One is a high-value, fluorinated heterocyclic building block. This compound is a critical intermediate in the synthesis of advanced pharmaceutical agents and agrochemicals, where the trifluoromethyl group imparts desirable metabolic stability and lipophilicity. It is primarily sought by R&D chemists and process development teams in the pharmaceutical, agrochemical, and advanced materials sectors for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: Key synthon for the development of novel drug candidates, particularly in central nervous system (CNS) and oncology research.
• Agrochemical Synthesis: Used in the creation of advanced herbicides and pesticides, leveraging the bioactivity of the carbazole scaffold.
• Material Science Research: Serves as a precursor for organic electronic materials, such as charge-transport layers or light-emitting components.
• Chemical Biology Probes: Utilized in the design of fluorescent tags or molecular probes for studying biological processes.
• Academic & Contract Research: Employed in university and CRO laboratories for methodological studies and novel synthetic route exploration.
• Fine Chemical Production: Acts as a building block for the custom synthesis of specialty chemicals for various industrial applications.

Basic Information

Product Name	6-(Trifluoromethyl)-2,3,4,9-Tetrahydro-1H-Carbazol-1-One
CAS No.	297763-74-7
Molecular Formula	C₁₃H₁₀F₃NO
Molecular Weight	253.22 g/mol
Synonyms	6-(Trifluoromethyl)-1,2,3,4-tetrahydro-9H-carbazol-1-one; 1-Oxo-6-(trifluoromethyl)-1,2,3,4-tetrahydro-9H-carbazole; 6-Trifluoromethyl-2,3,4,9-tetrahydro-1H-carbazol-1-one; 6-Trifluoromethyl-1,2,3,4-tetrahydrocarbazol-1-one; 6-CF3-Tetrahydrocarbazolone; 297763-74-7; 6-(Trifluoromethyl)-2,3,4,9-tetrahydrocarbazol-1-one
EINECS	Contact for details

Quality Control

Our 6-(Trifluoromethyl)-2,3,4,9-Tetrahydro-1H-Carbazol-1-One is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR/IR for structural confirmation, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) detailing batch-specific results are available upon request, providing full traceability and quality assurance for your critical projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation by atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.