Description

Methyl 3-([(4-Fluorophenyl)Sulfonyl]Oxy)-4-Nitrobenzenecarboxylate is a specialized organic intermediate featuring a sulfonate ester linkage, which is critical for its role as a key building block in advanced synthetic chemistry. This compound matters for its precise reactivity, enabling the controlled introduction of functional groups in complex molecular architectures. It is primarily needed by research and development chemists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of potential drug candidates, particularly those targeting central nervous system (CNS) disorders or possessing sulfonamide-based pharmacophores.
• Agrochemical Synthesis: Used in the development of new-generation herbicides, fungicides, or insecticides, leveraging its nitro and sulfonate ester functionalities.
• Material Science Research: Serves as a monomer or cross-linking agent in the development of specialty polymers with specific optical or electronic properties.
• Chemical Biology Probes: Employed in the design and synthesis of activity-based probes (ABPs) for studying enzyme function and mechanism.
• Organic Synthesis Building Block: Utilized in palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Heck) for constructing biaryl systems common in many functional materials.
• Dye and Pigment Intermediate: Acts as a key component in the synthesis of complex nitroaromatic dyes and colorants.

Basic Information

Product Name	Methyl 3-([(4-Fluorophenyl)Sulfonyl]Oxy)-4-Nitrobenzenecarboxylate
CAS No.	297150-07-3
Molecular Formula	C14H10FNO7S
Molecular Weight	355.30 g/mol
Synonyms	Methyl 3-((4-Fluorophenyl)sulfonyloxy)-4-nitrobenzoate; Benzoic acid, 3-[(4-fluorophenyl)sulfonyl]oxy]-4-nitro-, methyl ester; 4-Nitro-3-((4-fluorophenyl)sulfonyloxy)benzoic acid methyl ester; Methyl 4-nitro-3-((4-fluorophenyl)sulfonyloxy)benzoate; 3-((4-Fluorobenzenesulfonyl)oxy)-4-nitrobenzoic acid methyl ester; Methyl 3-(p-fluorophenylsulfonyloxy)-4-nitrobenzoate; 297150-07-3
EINECS	Contact for details

Quality Control

Our production of Methyl 3-([(4-Fluorophenyl)Sulfonyl]Oxy)-4-Nitrobenzenecarboxylate adheres to stringent quality protocols to ensure batch-to-batch consistency and purity for sensitive R&D and scale-up processes. All materials are characterized using advanced analytical techniques including HPLC, NMR, and MS. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms to reference spectrum
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.