Description

(2E)-1-(4-Bromophenyl)-3-(2-Fluorophenyl)Prop-2-En-1-One is a high-purity, synthetic chalcone derivative characterized by its distinct bromo and fluoro substituents. This compound is a critical pharmaceutical intermediate and a versatile building block in advanced organic synthesis, valued for its defined stereochemistry and functional group reactivity. It is primarily utilized by R&D chemists and process development teams in the pharmaceutical, agrochemical, and material science industries for the development of novel active compounds.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of potential drug candidates, particularly in medicinal chemistry research for oncology, CNS, and anti-inflammatory targets.
• Organic Synthesis Building Block: Used in cross-coupling reactions, cyclization processes, and as a scaffold for creating complex heterocyclic compounds.
• Agrochemical Research: Employed in the development of new pesticides and herbicides, leveraging its halogenated structure for bioactivity.
• Material Science: Investigated as a monomer or precursor for specialty polymers and advanced organic electronic materials.
• Chemical Biology Probe: Utilized in biochemical assays and as a tool compound for studying enzyme inhibition or protein-ligand interactions.
• Academic & Contract Research: Supplied to universities and CROs for fundamental chemical research and custom synthesis projects.

Basic Information

Product Name	(2E)-1-(4-Bromophenyl)-3-(2-Fluorophenyl)Prop-2-En-1-One
CAS No.	297138-53-5
Molecular Formula	C15H10BrFO
Molecular Weight	305.14 g/mol
Synonyms	(E)-1-(4-Bromophenyl)-3-(2-fluorophenyl)prop-2-en-1-one; (E)-4-Bromo-2'-fluorochalcone; 2'-Fluoro-4-bromochalcone; (E)-3-(2-Fluorophenyl)-1-(4-bromophenyl)-2-propen-1-one; 1-(4-Bromophenyl)-3-(2-fluorophenyl)-2-propen-1-one, (E)-; 4-Bromo-2'-fluorochalcone; Chalcone, 4'-bromo-2-fluoro-; 297138-53-5
EINECS	Contact for details

Quality Control

Our (2E)-1-(4-Bromophenyl)-3-(2-Fluorophenyl)Prop-2-En-1-One is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high chemical purity and structural identity. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, handling and packaging should minimize exposure to direct light.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.