Description

L-2-(4-Bromophenyl)-1,3-Thiazolane-4-Carboxylic Acid is a high-purity chiral building block and advanced pharmaceutical intermediate. Its value lies in its unique thiazolane ring system and bromophenyl moiety, which are critical for constructing complex molecules with specific biological activity. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, particularly for the synthesis of novel active ingredients and for use in asymmetric synthesis.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of new drug candidates, particularly for central nervous system (CNS) and anti-infective agents.
• Agrochemical Synthesis: Used in the creation of novel pesticides and herbicides, where the bromophenyl group can be leveraged for further functionalization.
• Asymmetric Catalysis: Serves as a precursor or ligand in the development of chiral catalysts for stereoselective chemical reactions.
• Chemical Biology Research: Employed as a molecular probe or building block for studying enzyme mechanisms and protein-ligand interactions.
• Material Science: Potential use as a monomer or functional additive in the synthesis of specialty polymers with unique optical or electronic properties.
• Academic & Contract Research: A valuable reagent for universities and CROs (Contract Research Organizations) conducting synthetic methodology and medicinal chemistry projects.

Basic Information

Product Name	L-2-(4-Bromophenyl)-1,3-Thiazolane-4-Carboxylic Acid
CAS No.	294866-41-4
Molecular Formula	C10H10BrNO2S
Molecular Weight	288.16 g/mol
Synonyms	(2R)-2-(4-Bromophenyl)-1,3-thiazolidine-4-carboxylic acid; L-2-(p-Bromophenyl)thiazolidine-4-carboxylic acid; (4R)-2-(4-Bromophenyl)-1,3-thiazolidine-4-carboxylic acid; (R)-2-(4-Bromophenyl)thiazolidine-4-carboxylic acid; 294866-41-4; BRN 8283425; SCHEMBL218064
EINECS	Contact for details

Quality Control

Our production of L-2-(4-Bromophenyl)-1,3-Thiazolane-4-Carboxylic Acid adheres to stringent quality management protocols. Every batch is subjected to comprehensive analytical testing, including chiral purity analysis, to ensure it meets the exacting standards required for pharmaceutical R&D. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting purity, identity, and impurity profiles.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. For long-term storage, consider inert atmosphere conditions to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.