Description

7-Oxabicyclo[2.2.1]Hept-2-Ene,5,5,6-Trifluoro-,(1R,4S,6S)-Rel-(9Ci) is a high-value, stereochemically defined fluorinated oxabicyclic building block. This compound matters for its unique structural framework, which combines a rigid bicyclic core with strategically placed fluorine atoms, enabling precise modulation of molecular properties in advanced synthesis. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for creating novel active ingredients with enhanced metabolic stability, bioavailability, and binding selectivity.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the development of novel active pharmaceutical ingredients (APIs), particularly in antiviral, anticancer, and central nervous system (CNS) drug discovery programs.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the fluorinated bicyclic structure can contribute to improved lipophilicity and target activity.
• Advanced Material Precursor: Serves as a specialized monomer or cross-linking agent in the synthesis of high-performance polymers and resins with tailored thermal and chemical resistance.
• Ligand and Catalyst Development: Employed in organometallic chemistry and catalysis research to construct sophisticated, fluorinated ligand systems for asymmetric synthesis.
• Fluorine Chemistry Research: A valuable substrate for studying structure-activity relationships (SAR) and the effects of fluorine substitution on molecular conformation and reactivity.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of bespoke compounds for client-specific projects.

Basic Information

Product Name	7-Oxabicyclo[2.2.1]Hept-2-Ene,5,5,6-Trifluoro-,(1R,4S,6S)-Rel-(9Ci)
CAS No.	292820-75-8
Molecular Formula	C6H5F3O
Molecular Weight	150.10 g/mol
Synonyms	(1R,4S,6S)-5,5,6-Trifluoro-7-oxabicyclo[2.2.1]hept-2-ene; rel-(1R,4S,6S)-5,5,6-Trifluoro-7-oxabicyclo[2.2.1]hept-2-ene; 5,5,6-Trifluoro-7-oxabicyclo[2.2.1]hept-2-ene, (1R,4S,6S)-rel-; 7-Oxabicyclo[2.2.1]hept-2-ene, 5,5,6-trifluoro-, (1R,4S,6S)-rel-; Fluorinated Oxanorbornene Derivative; Trifluorinated 7-Oxanorbornene
EINECS	Contact for details

Quality Control

Every batch of 7-Oxabicyclo[2.2.1]Hept-2-Ene,5,5,6-Trifluoro-,(1R,4S,6S)-Rel-(9Ci) is produced and controlled under a strict quality management system. Our products undergo rigorous analytical testing, including chiral purity verification, to ensure compliance with exacting R&D and process chemistry standards. A comprehensive Certificate of Analysis (COA) detailing identity, purity (typically by GC/HPLC), enantiomeric excess, and impurity profile is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its highly volatile nature, ensure containers are securely sealed and stored upright. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to reference spectrum
Purity (GC/HPLC)	≥ 97.0% (Area %)
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.