Description

4-Bromo-2,3,5,6-Tetrafluorobenzylchloride is a highly functionalized benzyl halide derivative, serving as a critical building block in advanced organic synthesis. Its unique structure, featuring both bromine and chlorine substituents on a perfluorinated aromatic ring, makes it a versatile electrophile for introducing complex fluorinated motifs. This compound is essential for researchers and process chemists in the pharmaceutical and agrochemical industries developing novel active ingredients with enhanced metabolic stability and lipophilicity.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of fluorinated drug candidates, particularly for central nervous system (CNS) and oncology targets.
• Agrochemical Synthesis: Building block for creating novel herbicides, fungicides, and pesticides with improved environmental profile and efficacy.
• Liquid Crystal & OLED Materials: Used in the development of fluorinated components for electronic display and lighting technologies.
• Polymer Modification: Serves as a functional monomer or cross-linking agent for engineering high-performance, specialty fluoropolymers.
• Organic Synthesis Reagent: Employed in cross-coupling reactions (e.g., Suzuki, Stille) and nucleophilic substitution to construct complex aromatic systems.
• Positron Emission Tomography (PET) Tracer Development: Potential precursor for radiolabeling with fluorine-18 for diagnostic imaging agents.

Basic Information

Product Name	4-Bromo-2,3,5,6-Tetrafluorobenzylchloride
CAS No.	292621-54-6
Molecular Formula	C7H2BrClF4
Molecular Weight	277.44 g/mol
Synonyms	1-(Bromomethyl)-2,3,5,6-tetrafluoro-4-chlorobenzene; (4-Bromo-2,3,5,6-tetrafluorophenyl)methyl chloride; 2,3,5,6-Tetrafluoro-4-bromobenzyl chloride; α-Chloro-4-bromo-2,3,5,6-tetrafluorotoluene; 4-Bromo-2,3,5,6-tetrafluorobenzyl chloride; Benzene, 1-(bromomethyl)-2,3,5,6-tetrafluoro-4-chloro-
EINECS	Contact for details

Quality Control

Our 4-Bromo-2,3,5,6-Tetrafluorobenzylchloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and elemental analysis, to ensure high purity and batch-to-batch consistency. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming compliance with agreed specifications. We support development and scale-up with custom purity grades to meet specific R&D and cGMP requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for prolonged use or storage to maintain stability and purity. Keep away from strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.