Description

1-Bromo-3-Chloro-2,4,6-Trifluorobenzene is a high-purity, multi-halogenated benzene derivative designed for advanced synthetic chemistry. This compound serves as a critical building block for introducing specific halogen substitution patterns into complex molecular architectures. It is essential for researchers and process chemists in the pharmaceutical and agrochemical industries developing novel active ingredients, particularly for applications requiring precise electronic and steric tuning.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially for fluorine-containing drugs targeting CNS disorders, anti-infectives, and oncology.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and insecticides where the trifluoromethyl and halogen pattern enhance biological activity and environmental stability.
• Material Science Research: Serves as a monomer or functionalization agent in the creation of specialty polymers, liquid crystals, and organic electronic materials.
• Cross-Coupling Reactions: An excellent substrate for palladium-catalyzed reactions like Suzuki, Stille, and Buchwald-Hartwig amination, enabling complex biaryl and heterocyclic structure formation.
• Chemical Synthesis Building Block: Provides a versatile scaffold for further functional group transformations in medicinal and process chemistry R&D.

Basic Information

Product Name	1-Bromo-3-Chloro-2,4,6-Trifluorobenzene
CAS No.	292621-44-4
Molecular Formula	C6HBrClF3
Molecular Weight	243.42 g/mol
Synonyms	3-Chloro-1-bromo-2,4,6-trifluorobenzene; 2,4,6-Trifluoro-3-chlorobromobenzene; Benzene, 1-bromo-3-chloro-2,4,6-trifluoro-; 1-Bromo-3-chloro-2,4,6-trifluorobenzene; 292621-44-4
EINECS	Contact for details

Quality Control

Every batch of 1-Bromo-3-Chloro-2,4,6-Trifluorobenzene is manufactured and tested under a strict quality management system. We ensure compliance with relevant industry standards, and comprehensive analytical testing is performed using GC, HPLC, NMR, and GC-MS to verify identity, purity, and impurity profiles. A Certificate of Analysis (COA) detailing all test results is provided with each shipment to guarantee traceability and batch-to-batch consistency for your critical R&D and production needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong acids and incompatible materials. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or solid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 98.0% (Standard Grade)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.