Description

(R)-1-(3-Chlorophenyl)-2-Hydroxy-1-Propanone CAS NO 291275-46-2 is a chiral building block of significant importance in asymmetric synthesis. This compound serves as a key intermediate for the production of high-value, optically active pharmaceuticals and agrochemicals. It is primarily needed by research institutions and industrial manufacturers in the pharmaceutical, fine chemical, and agrochemical sectors for developing novel active ingredients.

Application

• Pharmaceutical Intermediate: A critical chiral synthon for the synthesis of enantiomerically pure active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and cardiovascular drug candidates.
• Agrochemical Synthesis: Used in the research and development of advanced, optically selective herbicides, fungicides, and insecticides.
• Fine Chemical Production: Employed as a precursor for complex molecules in perfumery, flavor chemistry, and specialty materials.
• Asymmetric Catalysis Research: Serves as a standard substrate or ligand precursor in academic and industrial research focused on developing new chiral catalysts and methodologies.
• Process Chemistry Development: Utilized for scaling up and optimizing synthetic routes to chiral targets in kilo-lab and pilot plant settings.

Basic Information

Product Name	(R)-1-(3-Chlorophenyl)-2-Hydroxy-1-Propanone
CAS No.	291275-46-2
Molecular Formula	C9H9ClO2
Molecular Weight	184.62 g/mol
Synonyms	(R)-3'-Chloro-2-Hydroxypropiophenone; (R)-1-(3-Chlorophenyl)-2-Hydroxypropan-1-one; (R)-2-Hydroxy-1-(3-chlorophenyl)propan-1-one; (R)-α-Hydroxy-3-chloropropiophenone; (R)-3-Chloro-α-hydroxypropiophenone; (R)-Enantiomer of 1-(3-Chlorophenyl)-2-hydroxy-1-propanone
EINECS	Contact for details

Quality Control

Our (R)-1-(3-Chlorophenyl)-2-Hydroxy-1-Propanone is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity analysis by HPLC, to ensure it meets the high standards required for advanced synthetic applications. Certificates of Analysis (COA) detailing identity, purity, and enantiomeric excess are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. The product is light-sensitive and should be handled accordingly.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.