Description

3,5-Diiodobenzonitrile is a versatile halogenated aromatic nitrile building block of significant interest in advanced organic synthesis. This compound matters for its role as a key intermediate in the development of pharmaceuticals, agrochemicals, and functional materials, where its diiodo substitution pattern enables precise cross-coupling reactions. It is primarily needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A crucial building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds targeting thyroid receptors or requiring halogenated aromatic cores.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and pesticides, where its structure contributes to biological activity.
• Material Science Precursor: Serves as a monomer or functionalization agent in the development of specialty polymers, liquid crystals, and organic electronic materials.
• Cross-Coupling Reactions: An excellent substrate for palladium-catalyzed reactions like Suzuki, Sonogashira, and Heck couplings, enabling the introduction of the benzonitrile moiety into complex systems.
• Organic Synthesis Research: A valuable reagent in academic and industrial R&D labs for method development and the construction of novel chemical entities.
• Ligand and Catalyst Development: Used to synthesize specialized ligands for metal complexes and catalysts.

Basic Information

Item	Detail
Product Name	3,5-Diiodobenzonitrile
CAS No.	289039-52-7
Molecular Formula	C7H3I2N
Molecular Weight	354.91 g/mol
Synonyms	3,5-Diiodobenzonitrile; 3,5-Diiodo-benzonitrile; Benzonitrile, 3,5-diiodo-; 3,5-Diiodophenyl cyanide; 3,5-Bis(iodo)benzonitrile; 3,5-DIBN; AI3-52062; ZINC000004057756; BCP31933; SCHEMBL1180621
EINECS	Contact for details

Quality Control

Our 3,5-Diiodobenzonitrile is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Heavy Metals	< 10 ppm
Residue on Ignition	< 0.1%
Water Content (KF)	< 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.