Description

5''-Fluoro-2''-Hydroxy-3''-Nitropropiophenone is a specialized fluorinated aromatic ketone intermediate with a nitro and hydroxyl substituent pattern. This compound is valued for its unique molecular scaffold, which serves as a critical building block in advanced organic synthesis. It is primarily required by research and development chemists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and complex molecules.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of fluorinated drug candidates, particularly those targeting central nervous system (CNS) disorders and anti-inflammatory applications.
• Agrochemical Research: Used in the development of new herbicides and pesticides, where the fluorine atom enhances biological activity and metabolic stability.
• Organic Synthesis Building Block: Employed in constructing complex heterocyclic compounds and fine chemicals due to its reactive ketone, nitro, and phenolic hydroxyl groups.
• Material Science Research: Potential monomer or intermediate for synthesizing specialty polymers and advanced organic materials.
• Chemical Reference Standard: Serves as an analytical standard for quality control and method development in laboratories.

Basic Information

Product Name	5''-Fluoro-2''-Hydroxy-3''-Nitropropiophenone
CAS No.	288401-12-7
Molecular Formula	C9H8FNO4
Molecular Weight	213.16 g/mol
Synonyms	1-(5-Fluoro-2-hydroxy-3-nitrophenyl)propan-1-one; 3'-Nitro-5'-fluoro-2'-hydroxypropiophenone; 5-Fluoro-2-hydroxy-3-nitropropiophenone; Propiophenone, 5'-fluoro-2'-hydroxy-3'-nitro-; 288401-12-7; 5'-Fluoro-2'-hydroxy-3'-nitropropiophenone
EINECS	Contact for details

Quality Control

Our 5''-Fluoro-2''-Hydroxy-3''-Nitropropiophenone is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity and NMR/IR for structural confirmation, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) detailing all specifications are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). This material is light-sensitive (store away from light) and may be hygroscopic (moisture-sensitive). Keep away from strong acids/bases and oxidizing agents.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.