Description

5'-Chloro-2'-Hydroxy-4'-Methyl-3'-Nitroacetophenone is a specialized nitro-substituted acetophenone derivative that serves as a critical synthetic intermediate in advanced organic synthesis. Its unique substitution pattern makes it a valuable building block for constructing complex molecular architectures, particularly in the pharmaceutical and agrochemical sectors. This high-purity compound is essential for research and development chemists and process scale-up teams requiring reliable, high-quality raw materials for the synthesis of active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly those with nitro-aromatic or chlorinated phenol motifs.
• Agrochemical Synthesis: Building block for developing herbicides, fungicides, and insecticides, leveraging its nitro and chloro functional groups.
• Dye and Pigment Manufacturing: Intermediate in the production of specialized azo dyes and organic pigments where lightfastness and color properties are critical.
• Organic Synthesis Research: Versatile starting material for academic and industrial R&D in heterocyclic chemistry and material science.
• Ligand and Catalyst Development: Used to synthesize chelating ligands for metal complexes in catalytic applications.
• Polymer Chemistry: Monomer or modifier for creating polymers with specific nitro-aromatic functionalities.

Basic Information

Product Name	5'-Chloro-2'-Hydroxy-4'-Methyl-3'-Nitroacetophenone
CAS No.	288401-07-0
Molecular Formula	C9H8ClNO4
Molecular Weight	229.62 g/mol
Synonyms	1-(5-Chloro-2-hydroxy-4-methyl-3-nitrophenyl)ethan-1-one; 3'-Nitro-5'-chloro-2'-hydroxy-4'-methylacetophenone; 2-Acetyl-6-chloro-3-methyl-4-nitrophenol; 5-Chloro-2-hydroxy-4-methyl-3-nitroacetophenone; 288401-07-0; Acetophenone, 5'-chloro-2'-hydroxy-4'-methyl-3'-nitro-
EINECS	Contact for details

Quality Control

Our 5'-Chloro-2'-Hydroxy-4'-Methyl-3'-Nitroacetophenone is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC, GC, and NMR, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, confirming compliance with agreed specifications. Our quality commitment supports applications requiring high-purity intermediates for GMP or research use.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. The compound may be light-sensitive; prolonged exposure to light should be avoided.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.