Description

1-(4-Fluorophenyl)-1H-Pyrrole-2-Carboxylic Acid is a high-value fluorinated heterocyclic building block essential for advanced organic synthesis. This compound is critical for researchers and manufacturers developing novel active pharmaceutical ingredients (APIs) and agrochemicals, where the introduction of fluorine atoms and specific ring systems can dramatically alter biological activity and metabolic stability. It is primarily utilized by the pharmaceutical, agrochemical, and specialty chemical industries for the research and production of new therapeutic and crop protection agents.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel drug candidates, particularly in medicinal chemistry programs targeting CNS disorders, inflammation, and oncology.
• Agrochemical Research: Serves as a crucial building block in the synthesis of new-generation herbicides, fungicides, and insecticides with enhanced efficacy and environmental profiles.
• Material Science Precursor: Used in the synthesis of advanced organic materials, such as ligands for catalysis or monomers for specialty polymers.
• Chemical Biology Probe: Employed in academic and industrial research to create molecular probes for studying enzyme function and biological pathways.
• Custom Synthesis & Contract Manufacturing: A fundamental starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the life sciences sector.

Basic Information

Product Name	1-(4-Fluorophenyl)-1H-Pyrrole-2-Carboxylic Acid
CAS No.	288251-67-2
Molecular Formula	C11H8FNO2
Molecular Weight	205.19 g/mol
Synonyms	1-(4-Fluorophenyl)-1H-pyrrole-2-carboxylic acid; 2-Carboxy-1-(4-fluorophenyl)pyrrole; 1H-Pyrrole-2-carboxylic acid, 1-(4-fluorophenyl)-; 4-Fluoro-1-(1H-pyrrol-2-yl)benzoic acid (tautomeric form); 288251-67-2; 1-(p-Fluorophenyl)pyrrole-2-carboxylic acid
EINECS	Contact for details

Quality Control

Our production of 1-(4-Fluorophenyl)-1H-Pyrrole-2-Carboxylic Acid adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. Each lot is analyzed using advanced chromatographic and spectroscopic techniques (HPLC, GC, NMR, IR) to confirm identity, potency, and impurity profiles. Certificates of Analysis (COA) detailing all specifications and test results are provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep the container sealed to prevent contamination and moisture absorption. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Any single impurity ≤ 0.5%; Total impurities ≤ 1.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.