Description

Naphthalene, 2-Fluorodecahydro-, (4Ar,8Ar)-Rel- (9Ci) is a fluorinated, saturated derivative of naphthalene, representing a high-value, structurally defined intermediate for advanced chemical synthesis. This compound matters for its role as a precise building block in the development of complex molecules, offering unique stereochemistry and fluorine substitution that can modulate biological activity and material properties. It is primarily needed by research institutions and industrial R&D teams in the pharmaceutical, agrochemical, and advanced materials sectors for applications in medicinal chemistry, catalyst development, and specialty polymer research.

Application

• Pharmaceutical Intermediate: Serves as a key chiral building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) and anti-infective drug candidates.
• Agrochemical Research: Used in the development of new-generation pesticides and herbicides, where the fluorine atom and rigid decahydronaphthalene core can enhance metabolic stability and target binding.
• Catalyst Ligand Synthesis: Acts as a precursor for sophisticated chiral ligands used in asymmetric catalysis, enabling the production of enantiomerically pure compounds.
• Advanced Material Monomer: Employed in the research of specialty polymers and liquid crystals, where its fused ring system and fluorine content can influence thermal stability and optical properties.
• Chemical Reference Standard: Supplied as a high-purity standard for analytical method development and quality control in laboratories.
• Organic Synthesis Reagent: Utilized in academic and industrial research for exploring new fluorination methodologies and constructing complex polycyclic frameworks.

Basic Information

Product Name	Naphthalene, 2-Fluorodecahydro-, (4Ar,8Ar)-Rel- (9Ci)
CAS No.	288144-12-7
Molecular Formula	C₁₀H₁₇F
Molecular Weight	156.24 g/mol
Synonyms	rel-(4aR,8aR)-2-Fluorodecahydronaphthalene; (4aR,8aR)-2-Fluoro-decahydronaphthalene; 2-Fluorodecahydronaphthalene (rel-(4aR,8aR)-isomer); 2-Fluoro-perhydronaphthalene; Fluorinated Decalin Derivative; 2-Fluoro-cis-Decahydronaphthalene (relative configuration); FLN Intermediate; Bicyclo[4.4.0]decane, 2-fluoro-, (4aR,8aR)-rel-
EINECS	Contact for details

Quality Control

Our Naphthalene, 2-Fluorodecahydro-, (4Ar,8Ar)-Rel- (9Ci) is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including chiral purity analysis by GC or HPLC, to ensure structural integrity and high chemical purity suitable for sensitive synthetic applications. Certificates of Analysis (COA) detailing identity, assay, enantiomeric excess, and impurity profiles are provided and can be tailored to meet specific customer or regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. For long-term storage under an inert atmosphere (e.g., nitrogen or argon) is recommended to maintain product stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 97.0%
Enantiomeric Excess (Chiral GC/HPLC)	≥ 99.0% (rel-(4aR,8aR)-isomer)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.