Description

Benzeneacetonitrile, α-(Diphenylmethylene)-4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)- is a specialized boronic ester derivative that serves as a critical synthetic intermediate in modern organic chemistry. Its value lies in its dual functionality, combining a reactive nitrile group with a versatile pinacol boronate ester, enabling efficient cross-coupling reactions. This compound is essential for researchers and process chemists in the pharmaceutical and agrochemical industries who are developing new active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of complex drug candidates, particularly via Suzuki-Miyaura cross-coupling reactions.
• Agrochemical Synthesis: Used in the research and development of novel pesticides and herbicides requiring specific aryl-boron functionalities.
• Material Science Research: Serves as a precursor for creating organic electronic materials, such as those used in OLEDs and semiconductors.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes and tags for studying biological processes.
• Catalyst Ligand Development: Utilized as a starting material for synthesizing novel ligand frameworks in transition metal catalysis.
• Custom Fine Chemical Production: A crucial reagent for contract research and manufacturing organizations (CROs/CMOs) producing bespoke organic compounds.

Basic Information

Product Name	Benzeneacetonitrile, α-(Diphenylmethylene)-4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)-
CAS No.	288105-07-7
Molecular Formula	C27H26BNO2
Molecular Weight	407.31 g/mol
Synonyms	4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-α-(diphenylmethylene)benzeneacetonitrile; 2-[4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)benzylidene]-2-phenylmalononitrile (alternative representation); (4-(2,2-Dicyano-1,1-diphenylethyl)phenyl)boronic acid pinacol ester; Boronic acid, B-[4-(α-cyano-α,α-diphenylmethyl)phenyl]-, pinacol ester; α-(Diphenylmethylene)-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzenecetonitrile.
EINECS	Contact for details

Quality Control

Our Benzeneacetonitrile, α-(Diphenylmethylene)-4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)- is produced under strict quality management protocols to ensure batch-to-batch consistency and high purity for research and scale-up applications. Each lot undergoes comprehensive analysis including HPLC for purity and NMR for structural confirmation. Certificates of Analysis (COA) detailing all specifications are provided and can be tailored to meet specific customer requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Due to its hygroscopic (moisture-sensitive) nature, it is recommended to handle the material under an inert atmosphere (e.g., nitrogen or argon) for prolonged storage or after opening to maintain stability and purity. Recommended storage temperature is 2-8°C for long-term stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.