Description

4-Bromo-2-Hydroxybenzonitrile is a versatile brominated aromatic nitrile compound that serves as a critical building block in advanced organic synthesis. Its unique structure, featuring both a bromine substituent and a phenolic hydroxyl group adjacent to a nitrile, makes it a valuable intermediate for constructing complex molecules. This compound is primarily sought by research and development chemists in the pharmaceutical and agrochemical industries for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly those with brominated aromatic cores.
• Agrochemical Synthesis: Used in the development of new herbicides, fungicides, and pesticides, leveraging its halogenated structure.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands in coordination chemistry and catalysis.
• Material Science Research: Employed in the synthesis of advanced polymers, liquid crystals, and organic electronic materials.
• Chemical Biology Probes: Useful for synthesizing molecular probes and tags due to its reactive bromine and nitrile functional groups.
• Custom Synthesis and Contract Manufacturing: A high-value intermediate for fine chemical and custom synthesis houses serving diverse R&D needs.

Basic Information

Product Name	4-Bromo-2-Hydroxybenzonitrile
CAS No.	288067-35-6
Molecular Formula	C7H4BrNO
Molecular Weight	198.02 g/mol
Synonyms	2-Hydroxy-4-bromobenzonitrile; 4-Bromo-2-cyanophenol; 4-Bromosalicylonitrile; 2-Cyano-4-bromophenol; 4-Bromo-2-hydroxybenzenecarbonitrile; Benzonitrile, 4-bromo-2-hydroxy-; 288067-35-6
EINECS	Contact for details

Quality Control

Our 4-Bromo-2-Hydroxybenzonitrile is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. A detailed Certificate of Analysis (COA) is provided with every shipment, ensuring traceability and compliance with your research or production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be amber glass or opaque.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.