Description

Methyl 3-Amino-3-[4-(Trifluoromethoxy)Phenyl]Propanoate is a high-value, non-natural amino acid derivative featuring a trifluoromethoxy phenyl group, which imparts unique physicochemical properties critical for advanced synthesis. This compound serves as a versatile and key chiral building block in pharmaceutical research and development, enabling the creation of complex molecules with enhanced metabolic stability and bioavailability. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing novel active ingredients.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of novel drug candidates, particularly in central nervous system (CNS) and metabolic disease research.
• Agrochemical Active Ingredient Synthesis: Used to develop advanced herbicides and pesticides with improved efficacy and environmental profiles.
• Chiral Ligand and Catalyst Development: Serves as a starting material for creating sophisticated ligands used in asymmetric catalysis.
• Peptidomimetics and Bioactive Molecule Construction: Incorporated into peptide backbones to enhance stability and binding affinity.
• Chemical Biology Probes: Utilized in the design of molecular probes for studying enzyme mechanisms and protein interactions.
• Material Science Research: Acts as a monomer or modifier in the development of specialty polymers with specific optical or electronic properties.

Basic Information

Product Name	Methyl 3-Amino-3-[4-(Trifluoromethoxy)Phenyl]Propanoate
CAS No.	287959-34-6
Molecular Formula	C11H12F3NO3
Molecular Weight	263.21 g/mol
Synonyms	Methyl 3-amino-3-[4-(trifluoromethoxy)phenyl]propionate; 3-Amino-3-[4-(trifluoromethoxy)phenyl]propionic acid methyl ester; β-Amino-β-[4-(trifluoromethoxy)phenyl]propionic acid methyl ester; Methyl β-amino-β-(4-trifluoromethoxyphenyl)propionate; (R/S)-Methyl 3-amino-3-(4-trifluoromethoxyphenyl)propanoate; 4-(Trifluoromethoxy)-β-alanine methyl ester; Alanine derivative, N-(4-trifluoromethoxyphenyl)-, methyl ester
EINECS	Contact for details

Quality Control

Our production of Methyl 3-Amino-3-[4-(Trifluoromethoxy)Phenyl]Propanoate adheres to stringent quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis for enantiomeric excess (where applicable), and NMR/IR for structural confirmation, to ensure consistent identity, purity, and performance. We support cGMP and ISO 9001 standards for pharmaceutical intermediates. A detailed Certificate of Analysis (COA) is provided with every shipment, and custom specifications for research or commercial scale are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	Contact for details (racemic or enantiopure grades available)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.