Description

1-Methyl-2-Oxocyclobutane-1-Carbonitrile is a versatile and high-purity cyclobutane derivative, serving as a critical building block in advanced organic synthesis. Its unique strained-ring structure and functional groups make it a valuable precursor for developing novel compounds with specific biological and material properties. This intermediate is essential for research and development chemists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to create innovative products.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in the development of compounds with constrained ring systems.
• Agrochemical Research: Used in the creation of new herbicides, fungicides, and insecticides, leveraging its reactive nitrile and ketone functionalities.
• Material Science Precursor: Employed in the development of specialty polymers and advanced materials where the cyclobutane ring imparts specific thermal or mechanical properties.
• Organic Synthesis Building Block: Facilitates complex multi-step syntheses, including cycloaddition reactions and ring-expansion transformations in academic and industrial R&D settings.
• Ligand and Catalyst Development: Acts as a precursor for chiral ligands or metal-organic frameworks (MOFs) used in asymmetric catalysis.

Basic Information

Product Name	1-Methyl-2-Oxocyclobutane-1-Carbonitrile
CAS No.	287958-89-8
Molecular Formula	C6H7NO
Molecular Weight	109.13 g/mol
Synonyms	1-Methyl-2-oxocyclobutanecarbonitrile; 1-Cyano-1-methylcyclobutan-2-one; 1-Methyl-2-oxocyclobutyl cyanide; 2-Oxo-1-methylcyclobutanecarbonitrile; 1-Methylcyclobutan-2-one-1-carbonitrile; α-Methyl-α-cyanocyclobutanone
EINECS	Contact for details

Quality Control

Our 1-Methyl-2-Oxocyclobutane-1-Carbonitrile is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. We provide comprehensive analytical data, including HPLC, GC, and NMR profiles, with each shipment. A Certificate of Analysis (COA) detailing identity, purity, and impurity limits is available for every lot to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. Keep away from incompatible materials such as strong bases and reducing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.