Description

(S)-1-(3-Chlorophenyl)-2-Hydroxy-1-Propanone is a chiral organic compound featuring a chlorinated aromatic ring and a secondary alcohol functional group. This specific stereochemistry makes it a valuable chiral building block and intermediate in the synthesis of more complex molecules. It is primarily sought after by research and development teams in the pharmaceutical and fine chemical industries. The compound's structure is pivotal for creating active pharmaceutical ingredients (APIs) and other high-value specialty chemicals.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and production of enantiomerically pure drugs, particularly those targeting central nervous system (CNS) disorders.
• Asymmetric Synthesis: Used as a precursor or catalyst ligand in stereoselective chemical reactions to construct molecules with defined three-dimensional structures.
• Agrochemical Research: Serves as a building block for developing novel, chiral active ingredients for crop protection products.
• Material Science: Potential intermediate in the synthesis of specialty polymers and liquid crystals where chirality influences material properties.
• Academic & Contract Research: Employed in university and CRO laboratories for methodological development and exploratory synthesis projects.
• Fine Chemical Production: Integral in the multi-step synthesis of complex fragrances, flavors, and other high-purity specialty chemicals.

Basic Information

Product Name	(S)-1-(3-Chlorophenyl)-2-Hydroxy-1-Propanone
CAS No.	287477-53-6
Molecular Formula	C9H9ClO2
Molecular Weight	184.62 g/mol
Synonyms	(S)-3'-Chloro-2-Hydroxypropiophenone; (S)-1-(3-Chlorophenyl)-2-Hydroxypropan-1-one; (S)-2-Hydroxy-1-(3-chlorophenyl)propan-1-one; (S)-α-Hydroxy-3-chloropropiophenone; (S)-3-Chloro-α-hydroxypropiophenone; (S)-CPHP; (S)-Enantiomer of 1-(3-Chlorophenyl)-2-hydroxypropan-1-one
EINECS	Contact for details

Quality Control

Our (S)-1-(3-Chlorophenyl)-2-Hydroxy-1-Propanone is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity assessment by HPLC, to ensure it meets the high standards required for advanced synthetic applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to guarantee traceability and consistency for your critical R&D and production processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (typically 15-25°C). Keep the container tightly sealed to protect from moisture. Store away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.