Description

2-Chloro-4,5-Difluorobenzenesulfonamide is a high-purity, multi-functional sulfonamide derivative serving as a critical building block in advanced organic synthesis. Its unique halogenated aromatic structure makes it an essential intermediate for developing active pharmaceutical ingredients (APIs) and specialty agrochemicals. This compound is particularly valuable for researchers and manufacturers in the pharmaceutical, agrochemical, and material science industries seeking to introduce specific sulfonamide and halogen functionalities into complex molecules.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel drug candidates, particularly in sulfonamide-based therapeutics.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides and fungicides, leveraging its difluoro and chloro substituents.
• Chemical Research & Development: Serves as a versatile building block in organic synthesis for creating complex aromatic sulfonamides.
• Material Science Precursor: Potential use in the synthesis of specialty polymers and functional materials requiring specific halogenated aromatic units.
• Ligand and Catalyst Development: Can be utilized to create novel ligands for catalytic systems or in metal-organic frameworks (MOFs).

Basic Information

Item	Details
Product Name	2-Chloro-4,5-Difluorobenzenesulfonamide
CAS No.	287172-64-9
Molecular Formula	C6H4ClF2NO2S
Molecular Weight	227.62 g/mol
Synonyms	2-Chloro-4,5-difluorobenzenesulfonamide; Benzenesulfonamide, 2-chloro-4,5-difluoro-; 4,5-Difluoro-2-chlorobenzenesulfonamide; 2-Chloro-4,5-difluorophenylsulfonamide; 287172-64-9; SCHEMBL2384221; ZINC000006068008; AKOS005258155
EINECS	Contact for details

Quality Control

Every batch of 2-Chloro-4,5-Difluorobenzenesulfonamide is produced under a strict quality management system. Our products undergo rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency meet the high standards required for synthetic applications. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.