Description

1-(4-(Trifluoromethoxy)Phenoxy)-4-(Methylsulfonyl)Benzene is a high-purity, advanced pharmaceutical intermediate characterized by its distinct trifluoromethoxy and methylsulfonyl functional groups. This compound is critical for the synthesis of complex molecules, offering valuable properties for enhancing drug efficacy and stability. It is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for developing new active ingredients.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) and anti-inflammatory drugs.
• Agrochemical Research: Used in the development of advanced herbicides and pesticides, where the trifluoromethoxy group can improve biological activity and environmental stability.
• Material Science: Serves as a monomer or precursor for specialty polymers and liquid crystals, contributing to unique thermal and optical properties.
• Organic Synthesis: Employed as a versatile reagent in cross-coupling reactions and for introducing sulfone and aryl ether functionalities into target molecules.
• Life Science Research: Utilized as a biochemical tool or probe in medicinal chemistry research for structure-activity relationship (SAR) studies.

Basic Information

Item	Detail
Product Name	1-(4-(Trifluoromethoxy)Phenoxy)-4-(Methylsulfonyl)Benzene
CAS No.	286844-91-5
Molecular Formula	C14H11F3O4S
Molecular Weight	332.30 g/mol
Synonyms	4-[(4-Trifluoromethoxy)phenoxy]phenyl methyl sulfone; 1-(4-(Trifluoromethoxy)phenoxy)-4-(methylsulfonyl)benzene; 4-Methylsulfonyl-4'-(trifluoromethoxy)diphenyl ether; [4-(Methylsulfonyl)phenoxy]-4-(trifluoromethoxy)benzene; Bis(4-(methylsulfonyl)phenyl) ether (related); p-(Trifluoromethoxyphenoxy)phenyl methyl sulfone
EINECS	Contact for details

Quality Control

Our 1-(4-(Trifluoromethoxy)Phenoxy)-4-(Methylsulfonyl)Benzene is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, confirming compliance with agreed specifications. Our quality commitment supports applications requiring GMP-grade intermediates and research chemicals.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong oxidizing agents and incompatible materials. For long-term storage, consider an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.