Description

3-tert-Butoxycarbonylamino-3-(3,4-Dimethoxy-Phenyl)-Propionic Acid is a high-purity, protected amino acid derivative that serves as a critical building block in advanced organic synthesis. Its primary value lies in enabling the controlled construction of complex peptide and small molecule structures, particularly in pharmaceutical research and development. This compound is essential for medicinal chemists and process development scientists working on new active pharmaceutical ingredients (APIs), especially within the fields of neuroscience and cardiology.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the synthesis of novel drug candidates targeting neurological and cardiovascular diseases.
• Peptide Synthesis: Used in solid-phase and solution-phase peptide synthesis (SPPS) to incorporate a protected tyrosine-like moiety into peptide chains.
• Protecting Group Chemistry: The tert-butoxycarbonyl (Boc) group provides orthogonal protection for the amine functionality in multi-step synthetic sequences.
• Chemical Biology Research: Employed in the design and synthesis of enzyme inhibitors, receptor ligands, and fluorescent probes for biological studies.
• Process Chemistry Development: Serves as a starting material or intermediate in the scale-up and optimization of API manufacturing routes under GMP conditions.
• Academic Research: A valuable reagent for universities and research institutes exploring new synthetic methodologies and bioactive compound libraries.

Basic Information

Product Name	3-tert-Butoxycarbonylamino-3-(3,4-Dimethoxy-Phenyl)-Propionic Acid
CAS No.	284492-37-1
Molecular Formula	C₁₆H₂₃NO₆
Molecular Weight	325.36 g/mol
Synonyms	Boc-3,4-Dimethoxy-DL-phenylalanine; N-(tert-Butoxycarbonyl)-3-(3,4-dimethoxyphenyl)alanine; 3-(3,4-Dimethoxyphenyl)-N-[(2-methyl-2-propanyl)oxycarbonyl]alanine; (RS)-2-((tert-Butoxycarbonyl)amino)-3-(3,4-dimethoxyphenyl)propanoic acid; Boc-DL-3,4-Dimethoxyphenylalanine; N-Boc-3,4-dimethoxy-DL-phenylalanine; 3-(Boc-amino)-3-(3,4-dimethoxyphenyl)propionic acid; DL-3,4-Dimethoxyphenylalanine N-Boc derivative
EINECS	Contact for details

Quality Control

Our 3-tert-Butoxycarbonylamino-3-(3,4-Dimethoxy-Phenyl)-Propionic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis, and identity confirmation via NMR and IR spectroscopy, to ensure it meets the stringent requirements for pharmaceutical R&D. Certificates of Analysis (COA) with full traceability are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The product is moisture-sensitive; keep the container tightly sealed in a dry environment. For long-term storage, consider storage under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.