Description

2-Ethylphenylzinc Iodide is a versatile organozinc reagent, a key building block in modern synthetic organic chemistry. Its primary value lies in enabling efficient carbon-carbon bond formation, particularly in Negishi cross-coupling reactions, which are critical for constructing complex molecular architectures. This high-purity reagent is essential for R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials industries seeking reliable and scalable synthetic pathways.

Application

• Negishi Cross-Coupling Reactions: A premier reagent for the palladium-catalyzed coupling with aryl, vinyl, or alkynyl halides to form biaryl and other complex structures.
• Pharmaceutical Intermediate Synthesis: Used in the precise construction of active pharmaceutical ingredients (APIs) and key chiral intermediates.
• Agrochemical Compound Development: Facilitates the synthesis of novel herbicides, fungicides, and insecticides with specific activity profiles.
• Ligand and Catalyst Preparation: Serves as a precursor for synthesizing specialized ligands and organometallic catalysts.
• Material Science Research: Employed in the creation of organic electronic materials, such as OLED and OFET components.
• Fine Chemical and Flavor/Fragrance Synthesis: Enables the production of high-value, structurally complex aromatic compounds.

Basic Information

Product Name	2-Ethylphenylzinc Iodide
CAS No.	282727-19-9
Molecular Formula	C8H9IZn
Molecular Weight	297.45 g/mol
Synonyms	(2-Ethylphenyl)zinc iodide; Zinc, (2-ethylphenyl)iodo-; o-Ethylphenylzinc iodide; 1-Ethyl-2-(iodozincio)benzene; 2-Ethylbenzenylzinc iodide; 2-Ethyl-C6H4-Zn-I; (o-Ethylphenyl)zinc iodide
EINECS	Contact for details

Quality Control

Every batch of 2-Ethylphenylzinc Iodide is manufactured and analyzed under strict quality protocols to ensure consistency and reliability for sensitive synthetic applications. Our products undergo rigorous quality testing, including titration for precise assay determination and advanced spectroscopic methods for identity and purity verification. Certificates of Analysis (COA) detailing batch-specific results are available upon request to support your quality management systems.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (argon or nitrogen) at 2-8°C to maintain stability and prevent degradation. Due to its highly volatile and easily oxidized nature, the reagent should be handled in a controlled, moisture-free environment using standard Schlenk or glovebox techniques.

Specification

Item	Specification
Appearance	Colorless to pale yellow solution
Identification (NMR)	Conforms to structure
Assay (Titration)	≥ 0.5 M in specified solvent (e.g., THF)
Purity (GC)	≥ 95% (organozinc species)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.