Description

Ethanone, 2,2,2-Trifluoro-1-Phenyl-, Conjugate Acid (9Ci) is a specialized fluorinated aromatic ketone derivative, serving as a key synthetic intermediate and building block in advanced organic chemistry. Its unique trifluoroacetyl group attached to a phenyl ring makes it a valuable precursor for introducing fluorinated motifs, which are critical for modulating the physical, chemical, and biological properties of target molecules. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical sectors, where the incorporation of fluorine atoms is a strategic approach to enhance metabolic stability, bioavailability, and binding affinity.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in developing fluorinated drug candidates for oncology, CNS disorders, and anti-infectives.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where fluorination improves lipophilicity and environmental stability.
• Material Science Precursor: Serves as a monomer or modifier in the synthesis of specialty polymers, coatings, and liquid crystals with enhanced thermal and chemical resistance.
• Organic Synthesis Reagent: Employed in Friedel-Crafts acylation and other coupling reactions to introduce the 2,2,2-trifluoro-1-phenylethanone moiety into complex molecular architectures.
• Fluorine Chemistry Research: A valuable reference standard and starting material in academic and industrial R&D focused on organofluorine chemistry and methodology development.

Basic Information

Product Name	Ethanone, 2,2,2-Trifluoro-1-Phenyl-, Conjugate Acid (9Ci)
CAS No.	282548-99-6
Molecular Formula	C8H5F3O
Molecular Weight	174.12 g/mol
Synonyms	2,2,2-Trifluoro-1-phenylethanone Conjugate Acid; α,α,α-Trifluoroacetophenone Conjugate Acid; Phenyl Trifluoromethyl Ketone Conjugate Acid; Trifluoroacetylbenzene Conjugate Acid; 1-Phenyl-2,2,2-trifluoroethanone Conjugate Acid; (Trifluoroacetyl)benzene Conjugate Acid; TFA Conjugate Acid; Benzoyltrifluoromethane Conjugate Acid
EINECS	Contact for details

Quality Control

Our Ethanone, 2,2,2-Trifluoro-1-Phenyl-, Conjugate Acid (9Ci) is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and FTIR, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality commitment aligns with cGMP principles where applicable, ensuring the material is suitable for demanding research and scale-up applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. This material may be moisture-sensitive; ensure containers are sealed tightly after each use to minimize exposure to atmospheric humidity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.