Description

2-[3-(Trifluoromethyl)Anilino]-4H-3,1-Benzoxazin-4-One is a high-value, specialized benzoxazinone derivative distinguished by its trifluoromethyl anilino substituent. This compound serves as a critical advanced pharmaceutical intermediate and a versatile building block in modern synthetic chemistry, enabling the development of novel active ingredients. It is primarily required by R&D and production teams in the pharmaceutical, agrochemical, and advanced materials sectors for creating compounds with enhanced biological activity and stability.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders, inflammation, and oncology.
• Agrochemical Research: Serves as a core scaffold for developing new-generation herbicides, fungicides, and insecticides, leveraging the stability imparted by the trifluoromethyl group.
• Organic Synthesis Building Block: Used in constructing complex heterocyclic compounds for material science and chemical research due to its reactive benzoxazinone core.
• Ligand and Catalyst Development: Employed in the design of specialized ligands for catalysis and molecular recognition applications.
• Fluorine Chemistry Studies: A valuable compound for research into the effects of fluorine substitution on molecular properties and bioactivity.

Basic Information

Item	Details
Product Name	2-[3-(Trifluoromethyl)Anilino]-4H-3,1-Benzoxazin-4-One
CAS No.	282529-88-8
Molecular Formula	C15H9F3N2O2
Molecular Weight	306.24 g/mol
Synonyms	2-[(3-Trifluoromethyl)phenylamino]-4H-3,1-benzoxazin-4-one; 2-(3-Trifluoromethyl-anilino)-4H-benzo[d][1,3]oxazin-4-one; 2-(alpha,alpha,α-Trifluoro-m-toluidino)-4H-3,1-benzoxazin-4-one; 282529-88-8; Benzoxazinone derivative with trifluoromethyl anilino group; N-(3-Trifluoromethylphenyl)-4-oxo-4H-3,1-benzoxazin-2-amine
EINECS	Contact for details

Quality Control

Our 2-[3-(Trifluoromethyl)Anilino]-4H-3,1-Benzoxazin-4-One is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure high purity and consistent chemical identity. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from incompatible materials such as strong bases and fluorides. For long-term storage, consider under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.