Description

5-Methoxy-1H-Indole-2-Boronic Acid is a high-value boronic acid derivative and a versatile building block in modern synthetic chemistry. Its core value lies in enabling the precise construction of complex indole-based molecular architectures through efficient cross-coupling reactions. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors who require reliable, high-purity intermediates for drug discovery and fine chemical synthesis.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and oncology.
• Suzuki-Miyaura Cross-Coupling Reactions: Serves as a critical boronic acid partner for constructing biaryl and heterobiaryl bonds, a fundamental reaction in medicinal chemistry.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and plant growth regulators with indole scaffolds.
• Material Science: Employed in the synthesis of organic electronic materials, such as OLEDs and conductive polymers, where the indole unit is functionalized.
• Chemical Biology Probes: Utilized to create labeled compounds and molecular probes for studying biological pathways and protein interactions.
• Academic & R&D: A valuable reagent for methodological development in organic synthesis and catalysis research within university and industrial laboratories.

Basic Information

Item	Detail
Product Name	5-Methoxy-1H-Indole-2-Boronic Acid
CAS No.	282528-61-4
Molecular Formula	C9H10BNO3
Molecular Weight	190.99 g/mol
Synonyms	5-Methoxyindole-2-boronic acid; 2-Borono-5-methoxy-1H-indole; (5-Methoxy-1H-indol-2-yl)boronic acid; 5-Methoxy-1H-indole-2-boronic acid pinacol ester (common derivative); 5-MeO-indole-2-BA; 282528-61-4; 5-Methoxy-2-indoleboronic acid
EINECS	Contact for details

Quality Control

Our 5-Methoxy-1H-Indole-2-Boronic Acid is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, NMR for structural confirmation, and elemental analysis, to ensure it meets the high standards required for research and commercial synthesis. Certificates of Analysis (COA) detailing all specifications are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥97.0% (Standard Grade)
Water Content (KF)	≤1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.