Description

(1-[(tert-Butoxy)Carbonyl]-5-Methyl-1H-Pyrrol-2-Yl)Boronic Acid is a high-purity, synthetically valuable boronic acid derivative. This compound serves as a critical building block in modern organic synthesis, particularly in cross-coupling reactions. It is primarily utilized by research and development teams in the pharmaceutical and agrochemical industries for the creation of novel active ingredients and complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key precursor in Suzuki-Miyaura cross-coupling reactions for synthesizing novel drug candidates, especially those containing pyrrole or heterocyclic motifs.
• Agrochemical Synthesis: Used in the research and development of advanced pesticides and herbicides, enabling the construction of complex bioactive molecules.
• Material Science Research: Employed in the synthesis of organic electronic materials, polymers, and ligands for catalysis due to its functional boronic acid group.
• Chemical Biology & Proteomics: Acts as a versatile handle for bioconjugation and the development of chemical probes and sensors.
• Academic & Contract Research: Essential for methodology development and exploratory synthesis in university and CRO laboratory settings.
• Scale-up Process Development: Serves as a starting material for optimizing synthetic routes from milligram to kilogram scale for commercial production.

Basic Information

Product Name	(1-[(tert-Butoxy)Carbonyl]-5-Methyl-1H-Pyrrol-2-Yl)Boronic Acid
CAS No.	282528-59-0
Molecular Formula	C10H16BNO4
Molecular Weight	225.05 g/mol
Synonyms	5-Methyl-1-Boc-pyrrole-2-boronic acid; 1-Boc-5-methyl-1H-pyrrole-2-boronic acid; 1-(tert-Butoxycarbonyl)-5-methyl-1H-pyrrole-2-boronic acid; 2-Borono-5-methyl-1-[(2-methylpropan-2-yl)oxycarbonyl]-1H-pyrrole; 1-N-Boc-5-methylpyrrole-2-boronic acid; tert-Butyl 5-methyl-2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrrole-1-carboxylate (pinacol ester precursor).
EINECS	Contact for details

Quality Control

Our (1-[(tert-Butoxy)Carbonyl]-5-Methyl-1H-Pyrrol-2-Yl)Boronic Acid is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles. We support cGMP and ISO compliant documentation for advanced pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) when possible to maintain stability and purity. Keep the container tightly sealed after each use.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥95% (Typical 97-99%)
Water Content (KF)	≤1.0%
Heavy Metals	<20 ppm
Residue on Ignition	<0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.