Description

6,8-Dioxabicyclo[3.2.1]Octane,2-Fluoro-1,5-Dimethyl-,(1R,2R,5R)-(9Ci) is a high-purity, stereochemically defined fluorinated bicyclic ether building block. This compound matters for its unique structural framework, which combines fluorine substitution with a rigid oxygen-containing bicyclic scaffold, offering valuable synthetic handles for modulating molecular properties. It is primarily needed by researchers and process chemists in the pharmaceutical and agrochemical industries for the development of novel active ingredients, where its specific stereochemistry and fluorine atom are critical for bioactivity and metabolic stability.

Application

• Pharmaceutical Intermediate: Serves as a key chiral synthon in the research and development of new drug candidates, particularly for central nervous system (CNS) and antiviral therapeutics.
• Agrochemical Synthesis: Used in the creation of advanced herbicides and pesticides, where the fluorine atom enhances lipophilicity and environmental stability.
• Material Science Research: Acts as a monomer or precursor for developing specialty polymers and advanced materials with specific thermal or chemical resistance properties.
• Ligand and Catalyst Development: Employed in organometallic chemistry to construct complex, chelating ligands for asymmetric catalysis.
• Fluorine Chemistry Studies: A valuable reference compound for investigating the stereoelectronic effects of fluorine in constrained, polycyclic ether systems.
• Fine Chemical Production: Utilized in multi-step syntheses of complex natural product analogs and other high-value specialty chemicals.

Basic Information

Product Name	6,8-Dioxabicyclo[3.2.1]Octane,2-Fluoro-1,5-Dimethyl-,(1R,2R,5R)-(9Ci)
CAS No.	281193-45-1
Molecular Formula	C8H13FO2
Molecular Weight	160.18 g/mol
Synonyms	(1R,2R,5R)-2-Fluoro-1,5-dimethyl-6,8-dioxabicyclo[3.2.1]octane; 2-Fluoro-1,5-dimethyl-6,8-dioxabicyclo[3.2.1]octane, (1R,2R,5R)-; (1R,2R,5R)-2-Fluoro-1,5-dimethyl-6,8-dioxabicyclo[3.2.1]octane (9CI); Fluorinated Bicyclic Ether; 281193-45-1; (1R,2R,5R)-rel-2-Fluoro-1,5-dimethyl-6,8-dioxabicyclo[3.2.1]octane
EINECS	Contact for details

Quality Control

Our production of 6,8-Dioxabicyclo[3.2.1]Octane,2-Fluoro-1,5-Dimethyl-,(1R,2R,5R)-(9Ci) adheres to stringent quality management protocols. Each batch undergoes comprehensive analytical testing, including chiral purity verification, to ensure it meets the exacting standards required for advanced synthetic applications. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its highly volatile and easily oxidized nature, it is recommended to store under an inert atmosphere (e.g., nitrogen or argon) for long-term stability. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.