Description

Benzeneacetaldehyde, 4-Fluoro-α-Methyl-, (Alphas)- (9Ci) is a specialized fluorinated aromatic aldehyde derivative, serving as a high-value chiral building block in advanced organic synthesis. Its core value proposition lies in the precise introduction of both fluorine and a chiral methyl group onto the phenylacetaldehyde scaffold, enabling the fine-tuning of molecular properties for target applications. This compound is critically needed by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key chiral precursor in the synthesis of fluorinated drug candidates, particularly in central nervous system (CNS) and anti-inflammatory therapeutic areas.
• Agrochemical Synthesis: Used to construct advanced intermediates for novel pesticides and herbicides, where the fluorine atom enhances bioavailability and metabolic stability.
• Ligand and Catalyst Development: Serves as a starting material for creating chiral ligands and organocatalysts used in asymmetric synthesis.
• Flavor and Fragrance Chemistry: Employed in the research and development of complex aromatic molecules due to its specific substituted benzaldehyde structure.
• Material Science Research: Acts as a monomer or functionalization agent in the development of specialty polymers with tailored optical or electronic properties.
• Academic and R&D Laboratories: Essential for methodological studies in organic chemistry, particularly in reactions involving fluorinated carbonyl compounds.

Basic Information

Item	Detail
Product Name	Benzeneacetaldehyde, 4-Fluoro-α-Methyl-, (Alphas)- (9Ci)
CAS No.	279683-49-7
Molecular Formula	C9H9FO
Molecular Weight	152.16 g/mol
Synonyms	(S)-4-Fluoro-α-methylbenzeneacetaldehyde; (S)-2-(4-Fluorophenyl)propanal; 4-Fluoro-α-methylbenzeneacetaldehyde, (S)-; (αS)-4-Fluoro-α-methylbenzenecetaldehyde; p-Fluoro-α-methylphenylacetaldehyde, (S)-; (S)-1-(4-Fluorophenyl)propanal; (S)-4-Fluoro-2-phenylpropanal; A fluorinated chiral phenylacetaldehyde derivative
EINECS	Contact for details

Quality Control

Every batch of Benzeneacetaldehyde, 4-Fluoro-α-Methyl-, (Alphas)- (9Ci) is produced and tested under a strict quality management system. We provide comprehensive Certificates of Analysis (COA) that detail chiral purity, chemical purity, and identity confirmation. Our quality protocols are designed to meet the stringent requirements of cGMP for pharmaceutical intermediates and ensure consistency for research and scale-up applications.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) in a cool, dry, and well-ventilated place. Recommended storage temperature is 2-8°C for long-term stability. Allow the container to reach room temperature before opening to minimize moisture ingress.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.