Description

1-Piperidineacetic Acid, 3,4-Dihydroxy-5-Propyl-, (3S,4S,5R)- (9Ci) is a high-purity, stereochemically defined piperidine derivative of significant interest in advanced organic synthesis. This compound matters as a sophisticated chiral building block, enabling the development of novel molecules with precise three-dimensional structures. It is primarily needed by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of potential active ingredients and complex intermediates.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of novel therapeutic agents, particularly in central nervous system (CNS) and metabolic disorder drug candidates.
• Agrochemical Synthesis: Used in the construction of advanced, stereoselective pesticide and herbicide molecules to enhance efficacy and environmental profile.
• Asymmetric Catalysis Ligand Precursor: Serves as a starting material for synthesizing novel chiral ligands used in asymmetric hydrogenation and other catalytic transformations.
• Chemical Biology Probe Development: Employed in the design and synthesis of molecular probes for studying enzyme mechanisms and biological pathways.
• Academic & Institutional Research: A valuable compound for universities and research institutes exploring new synthetic methodologies and structure-activity relationships (SAR).
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for client-specific projects requiring high-purity, complex intermediates.

Basic Information

Product Name	1-Piperidineacetic Acid, 3,4-Dihydroxy-5-Propyl-, (3S,4S,5R)- (9Ci)
CAS No.	277298-32-5
Molecular Formula	C10H19NO4
Molecular Weight	217.26 g/mol
Synonyms	(3S,4S,5R)-3,4-Dihydroxy-5-propylpiperidine-1-acetic acid; 5-Propyl-3,4-dihydroxypiperidine-1-acetic acid (stereoisomer); (3S,4S,5R)-5-Propyl-3,4-dihydroxy-1-piperidineacetic acid; 1-Piperidineacetic acid, 3,4-dihydroxy-5-propyl-, (3S,4S,5R)-; Stereoisomer of 277298-32-5; Chiral piperidine acetic acid derivative; Propyl-dihydroxy-piperidineacetic acid
EINECS	Contact for details

Quality Control

Our 1-Piperidineacetic Acid, 3,4-Dihydroxy-5-Propyl-, (3S,4S,5R)- (9Ci) is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for research and development applications. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available upon request to support your regulatory and quality assurance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under anhydrous conditions. For long-term storage, consider storing under an inert atmosphere such as argon or nitrogen.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.